The utility of bank voles for studying prion disease

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The utility of bank voles for studying prion disease

The transmission of prions between species is often an inefficient course of as a result of species barrier, which represents incompatibility between prion seed and substrate molecules. Financial institution voles (Myodes glareolus) are an exception to this rule, as they’re prone to a various vary of prion strains from many alternative animal species.

Particularly, financial institution voles will be effectively contaminated with most forms of human prions and have performed a essential position in validating variably protease-sensitive prionopathy (VPSPr) and sure types of Gerstmann-Sträussler-Scheinker (GSS) illness as bona fide prion issues reasonably than non-transmissible proteinopathies. The financial institution vole prion protein (BVPrP) confers a “common prion acceptor” phenotype when expressed in mice and when used as a substrate for in vitro prion amplification assays, indicating that the distinctive prion transmission properties of financial institution voles are mediated by BVPrP. Over-expression of BVPrP in mice can even promote the spontaneous growth of prion illness, indicating that BVPrP is intrinsically vulnerable to each spontaneous and template-directed misfolding.

Right here, we focus on the utility of financial institution voles and BVPrP for prion analysis and the way they’ve supplied new instruments for establishing fast animal bioassays, modeling spontaneous prion illness, standardizing prion diagnostics, and understanding the molecular foundation of the species barrier. Right here we have now utilized a mix of translating ribosome affinity purification and ribosome profiling to determine biologically related prion-induced modifications throughout illness development in a cell-type particular and genome-wide method. Terminally diseased mice with extreme neurological signs confirmed in depth alterations in astrocytes and microglia. Surprisingly, we detected solely minor modifications within the translational profiles of neurons. Prion-induced alterations in glia overlapped with these recognized in different neurodegenerative illnesses, suggesting that related occasions happen in a broad spectrum of pathologies.

Pressure variation in remedy and prevention of human prion illnesses

Transmissible spongiform encephalopathies or prion illnesses describe quite a few completely different human issues that differ of their scientific phenotypes, that are nonetheless united by their transmissible nature and customary pathology.

Medical variation within the absence of a standard infectious agent is believed to be encoded by completely different conformations of the misfolded prion protein. This misfolded protein is the goal of strategies designed to stop illness transmission in a surgical setting and discount of the misfolded seed or stopping its continued propagation have been the main target of therapeutic methods. It’s subsequently doable that pressure variation might affect the efficacy of prevention and remedy approaches. Traditionally, an understanding of prion illness transmission and pathogenesis has been centered on analysis instruments developed utilizing agriculturally related strains of prion illness.

Nevertheless, an elevated understanding of the molecular biology of human prion issues has highlighted variations not solely between completely different types of the illness affecting people and animals but additionally inside illnesses resembling Creutzfeldt-Jakob Illness (CJD), which is represented by a number of sporadic CJD particular conformations and an extra conformation related to variant CJD. On this chapter we are going to focus on whether or not prion pressure variation can have an effect on the efficacy of strategies used to decontaminate prions and whether or not pressure variation in pre-clinical fashions of prion illness can be utilized to determine therapeutic methods which have the very best likelihood of success within the clinic.

 The utility of bank voles for studying prion disease
The utility of bank voles for studying prion disease

Dealing with of endoscopic tools after use within the case of a affected person with suspected prion illness

Introduction: Prion illnesses are slow-acting, neurodegenerative illnesses present in people and lots of species of animals. Though they happen very not often in people, at the moment, a rise in this sort of illness is being noticed, in all probability on account of publicity to infectious prions inflicting BSE illness in cows.

Goal: The goal of the procedures described within the article is to attenuate the danger of human-to-human switch of all types of transmissible spongiform encephalopathy, together with variant CJD (vCJD) by contaminated medical tools.
Transient description of the state of data: All illnesses brought on by prions, known as transmissible spongiform encephalopathies, are deadly. They’re characterised by a protracted growth interval (as much as a number of a long time). Monumental issues are related with the danger of transferring prions from affected person to affected person on the floor of devices utilized in medical procedures. Laboratory checks point out that commonplace disinfection and sterilization procedures could also be inadequate to fully take away infectious proteins from contaminated devices.

One of many strategies of an infection prevention includes taking tools used for surgical procedure inside the mind, tonsils or appendix, into quarantine till biopsy outcomes of those organs have been acquired that exclude, so far as doable, asymptomatic carriage of prions.

Human PRND(Prion-like protein doppel) ELISA Kit

EKF60403-5x96T 5x96T
EUR 2693.25

Human PRND(Prion-like protein doppel) ELISA Kit

EKF60403-96T 96T
EUR 567

Prnd ELISA Kit| Mouse Prion-like protein doppel ELISA Kit

EF013205 96 Tests
EUR 826.8

Cow Prion-like protein doppel (PRND) ELISA Kit

abx516386-96tests 96 tests
EUR 1093.2

PRND ELISA Kit| Bovine Prion-like protein doppel ELISA Kit

EF011784 96 Tests
EUR 826.8

ELISA kit for Mouse Prion-like protein doppel

EK3191 96 tests
EUR 804
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Prion-like protein doppel in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Human Prion-like protein doppel

EK3192 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human Prion-like protein doppel in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse Prion-like protein doppel (PRND) ELISA Kit

abx254932-96tests 96 tests
EUR 886.8

Human Prion-like protein doppel (PRND) ELISA Kit

abx250777-96tests 96 tests
EUR 801.6

Mouse Prion-like protein doppel (PRND) ELISA Kit

RK13644 96T
EUR 280

Human Prion-like protein doppel (PRND) ELISA Kit

RK12169 96T
EUR 280

Prion-Like Protein Doppel (PRND) Protein

20-abx263269
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Mouse Prion-like protein doppel (Prnd)

1-CSB-BP886153MO
  • EUR 711.60
  • EUR 306.00
  • EUR 1777.20
  • EUR 949.20
  • EUR 1303.20
  • EUR 416.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Prion-like protein doppel(Prnd) expressed in Baculovirus

Prion-Like Protein Doppel (Prnd) Antibody

abx236794-100ug 100 ug
EUR 661.2

Prion-Like Protein Doppel (PRND) Antibody

20-abx322158
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Prion-Like Protein Doppel (PRND) Antibody

20-abx320384
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Prion-Like Protein Doppel (PRND) Antibody

20-abx006423
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Prion-like protein doppel Recombinant Protein

92-424 0.05 mg
EUR 651.3
Description: Prion-like protein doppel is a 152 amino acids protein that belongs to the prion family. The protein encoded by this gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. It is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.

Human Prion-like protein doppel Recombinant Protein C-6 His Tag

IHUPPDRC6HIS50UG each
EUR 762
Description: Human Prion-like protein doppel Recombinant Protein C-6 His Tag

ELISA kit for Sheep Major prion protein (PRNP)

KTE110020-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Major prion protein (PRNP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Major prion protein (PRNP)

KTE110020-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Major prion protein (PRNP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Major prion protein (PRNP)

KTE110020-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Major prion protein (PRNP) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Shadow of prion protein (SPRN)

KTE110008-48T 48T
EUR 424.8
Description: Quantitative sandwich ELISA for measuring Sheep Shadow of prion protein (SPRN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Shadow of prion protein (SPRN)

KTE110008-5platesof96wells 5 plates of 96 wells
EUR 2702.4
Description: Quantitative sandwich ELISA for measuring Sheep Shadow of prion protein (SPRN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Sheep Shadow of prion protein (SPRN)

KTE110008-96T 96T
EUR 686.4
Description: Quantitative sandwich ELISA for measuring Sheep Shadow of prion protein (SPRN) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Doppel Antibody / PRND

RQ4601 100ug
EUR 356.15
Description: Prion protein 2 (dublet), also known as PRND, or Doppel protein, is a protein which in humans is encoded by the PRND gene. It is mapped to 20p13. This gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.

Sheep Bcl2 Like Protein 11 (BCL2L11) ELISA Kit

abx364121-96tests 96 tests
EUR 1111.2

Sheep SPARC Like Protein 1 (SPARCL1) ELISA Kit

abx364068-96tests 96 tests
EUR 1111.2

Sheep Angiopoietin Like Protein 3 (ANGPTL3) ELISA Kit

abx364286-96tests 96 tests
EUR 1111.2

Sheep Angiopoietin Like Protein 6 (ANGPTL6) ELISA Kit

abx364343-96tests 96 tests
EUR 1111.2

Sheep Angiopoietin Like Protein 1 (ANGPTL1) ELISA Kit

abx364423-96tests 96 tests
EUR 1111.2

Human Prion Protein ELISA Kit

IHUPRNPKT each
EUR 700
Description: Human Prion Protein ELISA Kit

Mouse Prion Protein ELISA Kit

IMSPRNPKT each
EUR 718
Description: Mouse Prion Protein ELISA Kit

Sheep Dihydropyrimidinase Like Protein 2 (DPYSL2) ELISA Kit

abx364359-96tests 96 tests
EUR 1111.2

Rat Prion Protein (PRNP) ELISA Kit

20-abx258974
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Cow Prion Protein (PRNP) ELISA Kit

abx521103-96tests 96 tests
EUR 1093.2

Dog Prion Protein (PRNP) ELISA Kit

abx521105-96tests 96 tests
EUR 1093.2

Pig Prion Protein (PRNP) ELISA Kit

abx521108-96tests 96 tests
EUR 1093.2

Rat Prion Protein (PRNP) ELISA Kit

abx521109-96tests 96 tests
EUR 801.6

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x96wellstestplate 1x96-wells test plate
EUR 822.24
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-5x96wellstestplate 5x96-wells test plate
EUR 3340.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

4-SEB680Ra
  • EUR 6210.00
  • EUR 3280.80
  • EUR 823.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Prion Protein (PRNP) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Prion Protein (PRNP) ELISA Kit

EKU11355-48T 48T
EUR 603.26

Rat Prion Protein (PRNP) ELISA Kit

EKU11355-5x96T 5x96T
EUR 4093.55

Rat Prion Protein (PRNP) ELISA Kit

EKU11355-96T 96T
EUR 861.8

Rat Prion Protein (PRNP) ELISA Kit

EKN52466-48T 48T
EUR 375.41

Rat Prion Protein (PRNP) ELISA Kit

EKN52466-5x96T 5x96T
EUR 2547.43

Rat Prion Protein (PRNP) ELISA Kit

EKN52466-96T 96T
EUR 536.3

Rat PRNP(Prion Protein) ELISA Kit

ELK7722-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PRNP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PRNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat PRNP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat PRNP in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat PRNP(Prion Protein) ELISA Kit

ELK7722-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PRNP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PRNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat PRNP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat PRNP in the samples is then determined by comparing the OD of the samples to the standard curve.

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-48T 48T
EUR 403.2

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-96T 96T
EUR 640.8

Mouse Prion Protein (PRNP) ELISA Kit

abx255159-96tests 96 tests
EUR 895.2

Human Prion Protein (PRNP) ELISA Kit

abx251835-96tests 96 tests
EUR 895.2

Human Prion Protein (PRNP) ELISA Kit

abx573091-96tests 96 tests
EUR 801.6

Mouse Prion Protein (PRNP) ELISA Kit

abx571234-96tests 96 tests
EUR 801.6

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

20-abx156738
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Prion Protein (PRNP) ELISA Kit

20-abx156832
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

4-SEB680Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

4-SEB680Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Prion Protein ELISA Kit (PRNP)

RK02138 96 Tests
EUR 625.2

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-48Tests 48 Tests
EUR 600

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-96Tests 96 Tests
EUR 830.4

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-48Tests 48 Tests
EUR 613.2

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-96Tests 96 Tests
EUR 850.8

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-48Tests 48 Tests
EUR 626.4

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-96Tests 96 Tests
EUR 868.8

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-48Tests 48 Tests
EUR 640.8

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-96Tests 96 Tests
EUR 890.4

Mouse Prion Protein ELISA Kit (PRNP)

RK03137 96 Tests
EUR 625.2

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-48T 48T
EUR 453.92
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-96T 96T
EUR 648.38
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-48T 48T
EUR 465.47
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-96T 96T
EUR 664.97
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-48T 48T
EUR 432.3
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-96T 96T
EUR 617.5
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-48T 48T
EUR 443.3
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-96T 96T
EUR 633.3
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

EKL60110-5x96T 5x96T
EUR 3622.83

Human Prion Protein (PRNP) ELISA Kit

EKL60110-96T 96T
EUR 762.7

Mouse Prion Protein (PRNP) ELISA Kit

EKL60111-5x96T 5x96T
EUR 3713.55

Mouse Prion Protein (PRNP) ELISA Kit

EKL60111-96T 96T
EUR 781.8

Human Prion Protein(PRNP)ELISA Kit

QY-E01716 96T
EUR 433.2

Human Prion Protein (PRNP) ELISA Kit

DL-PRNP-Hu 96T
EUR 421
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DL-PRNP-Mu 96T
EUR 432
Description: tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu 96T
EUR 443
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu 96T
EUR 454
Description: tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

EKU08466-48T 48T
EUR 542.78

Mouse Prion Protein (PRNP) ELISA Kit

EKU08466-5x96T 5x96T
EUR 3683.15

Mouse Prion Protein (PRNP) ELISA Kit

EKU08466-96T 96T
EUR 775.4

Human Prion Protein (PRNP) ELISA Kit

EKU08509-48T 48T
EUR 527.66

Human Prion Protein (PRNP) ELISA Kit

EKU08509-5x96T 5x96T
EUR 3580.55

Human Prion Protein (PRNP) ELISA Kit

EKU08509-96T 96T
EUR 753.8

Human Prion Protein (PRNP) ELISA Kit

EKU11597-48T 48T
EUR 581.35

Human Prion Protein (PRNP) ELISA Kit

EKU11597-5x96T 5x96T
EUR 3944.88

Human Prion Protein (PRNP) ELISA Kit

EKU11597-96T 96T
EUR 830.5

Human Prion Protein (PRNP) ELISA Kit

EKU11967-48T 48T
EUR 633.5

Human Prion Protein (PRNP) ELISA Kit

EKU11967-5x96T 5x96T
EUR 4298.75

Human Prion Protein (PRNP) ELISA Kit

EKU11967-96T 96T
EUR 905

Human Prion Protein (PRNP) ELISA Kit

EKN53078-48T 48T
EUR 394.17

Human Prion Protein (PRNP) ELISA Kit

EKN53078-5x96T 5x96T
EUR 2674.73

Human Prion Protein (PRNP) ELISA Kit

EKN53078-96T 96T
EUR 563.1

Human Prion Protein (PRNP) ELISA Kit

EKN52708-48T 48T
EUR 361.55

Human Prion Protein (PRNP) ELISA Kit

EKN52708-5x96T 5x96T
EUR 2453.38

Human Prion Protein (PRNP) ELISA Kit

EKN52708-96T 96T
EUR 516.5

Mouse Prion Protein (PRNP) ELISA Kit

EKN49577-48T 48T
EUR 337.82

Mouse Prion Protein (PRNP) ELISA Kit

EKN49577-5x96T 5x96T
EUR 2292.35

Mouse Prion Protein (PRNP) ELISA Kit

EKN49577-96T 96T
EUR 482.6

Human Prion Protein (PRNP) ELISA Kit

EKN49620-48T 48T
EUR 328.44

Human Prion Protein (PRNP) ELISA Kit

EKN49620-5x96T 5x96T
EUR 2228.7

Human Prion Protein (PRNP) ELISA Kit

EKN49620-96T 96T
EUR 469.2

Mouse PRNP(Prion Protein) ELISA Kit

ELK5103-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PRNP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PRNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PRNP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PRNP in the samples is then determined by comparing the OD of the samples to the standard curve.

Mouse PRNP(Prion Protein) ELISA Kit

ELK5103-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse PRNP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse PRNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse PRNP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse PRNP in the samples is then determined by comparing the OD of the samples to the standard curve.

Human PRNP(Prion Protein) ELISA Kit

ELK5129-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PRNP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PRNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human PRNP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human PRNP in the samples is then determined by comparing the OD of the samples to the standard curve.

Human PRNP(Prion Protein) ELISA Kit

ELK5129-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PRNP. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PRNP. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human PRNP, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human PRNP in the samples is then determined by comparing the OD of the samples to the standard curve.

Bovine Prion Protein (PRNP) ELISA Kit

EKU12180-48T 48T
EUR 633.43

Bovine Prion Protein (PRNP) ELISA Kit

EKU12180-5x96T 5x96T
EUR 4298.28

Bovine Prion Protein (PRNP) ELISA Kit

EKU12180-96T 96T
EUR 904.9

Bovine Prion Protein (PRNP) ELISA Kit

EKN53290-48T 48T
EUR 394.17

Bovine Prion Protein (PRNP) ELISA Kit

EKN53290-5x96T 5x96T
EUR 2674.73

Conclusions: At any time when doable and justified, disposable-use devices must be used for invasive surgical procedure in sufferers with particular, clinically possible circumstances of CJD (vCJD). After use, these devices must be incinerated.

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