In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

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In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

Prion-like habits has been within the highlight because it was first related to the onset of mammalian neurodegenerative illnesses. Nevertheless, a rising physique of proof means that this mechanism may very well be behind the regulation of processes similar to transcription and translation in a number of species. Right here, we carry out a stringent computational survey to establish prion-like proteins within the human proteome. We detected 242 candidate polypeptides and computationally assessed their operate, protein-protein interplay networks, tissular expression, and their hyperlink to illness. Human prion-like proteins represent a subset of modular polypeptides broadly expressed throughout totally different cell varieties and tissues, considerably related to illness, embedded in extremely related interplay networks, and concerned within the stream of genetic data within the cell.

Our evaluation means that these proteins may play a related function not solely in neurological issues, but additionally in several types of most cancers and viral infections. Prion illnesses are quickly progressive neurodegenerative situations that may be tough to diagnose and are transmissible underneath particular circumstances. The authors will present background concerning prion illness and give attention to diagnostic instruments.Prion illness is brought on by misfolded prion protein. The three doable causes of prion illness embody sporadic (85%), genetic (10-15%), and purchased (<1%). Acquired prion illnesses embody kuru, iatrogenic, and variant Creutzfeldt-Jakob illness. Prion illnesses differ of their scientific manifestation, neuropathology, and diagnostic take a look at outcomes.

Quite a lot of latest diagnostic instruments have developed that enable extra dependable antemortem prognosis of prion illness similar to mind MRI and cerebrospinal fluid real-time quaking-induced conversion. Particular infectivity tips should be adopted when coping with central nervous system tissue, however solely normal precautions are wanted for routine scientific care of sufferers with prion illness.The one method to undoubtedly diagnose prion illness and decide its kind is by way of neuropathologic examination. Nevertheless, mind MRI and cerebrospinal fluid real-time quaking-induced conversion have drastically elevated diagnostic accuracy and are essential exams to make use of when evaluating sufferers with suspected prion illness.

Axonal modifications in experimental prion illnesses recapitulate these following constriction of postganglionic branches of the superior cervical ganglion: a comparability 40 years later.

The key neurological function of prion illnesses is a neuronal loss completed via both apoptosis or autophagy. On this evaluate, I in contrast axonal alterations in prion illnesses to these described 40 years earlier because of nerve ligation. I additionally demonstrated that autophagic vacuoles and autophagosomes are a significant a part of dystrophic neurites.

Moreover, I summarized the present standing of the autophagy in prion illnesses and hypothesize, that spongiform change might originate from the autophagic vacuoles. This conclusion must be supported by different strategies, specifically laser confocal microscopy. We noticed neuronal autophagic vacuoles in several phases of formation, and our interpretation of the ‘maturity’ of their formation might or might not equate to precise developmental phases. Initially, part of the neuronal cytoplasm was sequestrated inside double or a number of membranes (phagophores) and sometimes exhibited elevated electron-density.

The intracytoplasmic membranes shaped labyrinth-like buildings that counsel a multiplication of these membranes. The autophagic vacuoles then develop and ultimately, an enormous space of the cytoplasm was reworked right into a merging mass of autophagic vacuoles. Margaret R. Matthews revealed an extended treatise within the Philosophical Transactions of the Royal Society of London through which she had described in nice element the ultrastructure of postganglionic branches of the superior cervical ganglion within the rat following ligation of them. The earliest modifications noticed by Matthews between 6 h to 2 days within the proximal stump have been distensions of proximal axons. Analogously, in our fashions, an elevated variety of ‘common’ (spherical) and ‘irregular’ MVB and a few autophagic vacuoles have been noticed collectively, each processes have been comparable.

 In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.
In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

Prion protein quantification in human cerebrospinal fluid as a software for prion illness drug growth.

Discount of native prion protein (PrP) ranges within the mind is a beautiful technique for the remedy or prevention of human prion illness. Medical growth of any PrP-reducing therapeutic would require an acceptable pharmacodynamic biomarker: a sensible and sturdy methodology for quantifying PrP, and reliably demonstrating its discount within the central nervous system (CNS) of a residing affected person. Right here we consider the potential of ELISA-based quantification of human PrP in human cerebrospinal fluid (CSF) to function a biomarker for PrP-reducing therapeutics.

We present that CSF PrP is very delicate to plastic adsorption throughout dealing with and storage, however its loss may be minimized by the addition of detergent. We discover that blood contamination doesn’t have an effect on CSF PrP ranges, and that CSF PrP and hemoglobin are uncorrelated, collectively suggesting that CSF PrP is CNS derived, supporting its relevance for monitoring the tissue of curiosity and in step with excessive PrP abundance in mind relative to blood. In a cohort with managed pattern dealing with, CSF PrP displays good within-subject test-retest reliability (imply coefficient of variation, 13% in samples collected 8-11 wk aside), a sufficiently secure baseline to permit therapeutically significant reductions in mind PrP to be readily detected in CSF.

Major Prion Protein (CD230) Antibody

abx415315-01mg 0.1 mg
EUR 543.6

Major Prion Protein (CD230) Antibody

abx415316-01mg 0.1 mg
EUR 543.6

Prion Protein/CD230

CH23027 200 ul
EUR 553.2

Prion Protein (PrP) Antibody

abx120080-01ml 0.1 ml
EUR 944.4

Prion Protein(PrP) Antibody

48939-100ul 100ul
EUR 399.6

Prion Protein(PrP) Antibody

48939-50ul 50ul
EUR 286.8

PrP Antibody Prion protein

R30892 100 ug
EUR 356.15
Description: Prion protein, also known as CD230 and PrP, is a protein that in humans is encoded by the PRNP gene. Expression is predominantly in the nervous system but occurs to some degree in many other tissues throughout the body. Puckett et al.(1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PrP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. The protein is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6% similarity in amino acid sequences.

Prion protein Antibody (PrP)

R30893 100 ug
EUR 356.15
Description: Prion protein, also known as CD230 and PRP, is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al.(1991) identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru.

Prion protein Antibody (PrP)

R31881 100 ug
EUR 356.15
Description: PRNP (prion protein), also known as CD230 or PrP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. (1991) identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20. PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6% similarity in amino acid sequences.

PrP Antibody / Prion protein

RQ5040 100ul
EUR 356.15
Description: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. [RefSeq]

Prion Protein(PrP) Conjugated Antibody

C48939 100ul
EUR 476.4

Cluster of Differentiation 230 Prion Protein Disease Form (CD230 PrPSc) Antibody

abx414218-025mg 0.25 mg
EUR 710.4

Anti-Hu CD230 / Prion Purified

11-593-C025 0.025 mg
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Anti-Hu CD230 / Prion Purified

11-593-C100 0.1 mg
EUR 309.6

Prion Protein (PRNP) Antibody

20-abx174157
  • EUR 978.00
  • EUR 510.00
  • 1 mg
  • 200 ug

Prion Protein (PRNP) Antibody

abx120079-01ml 0.1 ml
EUR 1779.6

Prion Protein (PRNP) Antibody

20-abx114678
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Prion Protein (PRNP) Antibody

20-abx101113
  • EUR 493.20
  • EUR 159.60
  • EUR 1378.80
  • EUR 678.00
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Prion Protein (PRNP) Antibody

20-abx101114
  • EUR 510.00
  • EUR 159.60
  • EUR 1412.40
  • EUR 693.60
  • EUR 393.60
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Prion Protein (PRNP) Antibody

abx431521-200ul 200 ul
EUR 460.8

Polyclonal Prion Protein Antibody

APR12947G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Prion Protein . This antibody is tested and proven to work in the following applications:

Prion Protein 2 (PRND) Antibody

20-abx114679
  • EUR 878.40
  • EUR 477.60
  • 150 ul
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Prion Protein (PRNP) Antibody Pair

20-abx370619
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  • EUR 1429.20
  • 10 × 96 tests
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Prion Protein (PRNP) Antibody Pair

20-abx370620
  • EUR 2047.20
  • EUR 1312.80
  • 10 × 96 tests
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Prion Protein (PRNP) Antibody Pair

20-abx370621
  • EUR 1996.80
  • EUR 1279.20
  • 10 × 96 tests
  • 5 × 96 tests

Major Prion Protein (PRNP) Antibody

20-abx333875
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Major Prion Protein (PRNP) Antibody

20-abx319681
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Major Prion Protein (PRNP) Antibody

20-abx002019
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
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Anti-Prion protein PrP/PRNP Antibody

PB9783 100ug/vial
EUR 400.8

Anti-Prion protein PrP/PRNP Antibody

PA1794 100ug/vial
EUR 352.8

Anti-Prion protein PrP/PRNP Antibody

PA1795 100ug/vial
EUR 400.8

Major Prion Protein (PRNP) Antibody (HRP)

20-abx336435
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Shadow of Prion Protein (SPRN) Antibody

abx032300-400ul 400 ul
EUR 627.6

Shadow of Prion Protein (SPRN) Antibody

abx032300-80l 80 µl
EUR 343.2

Shadow Of Prion Protein (SPRN) Antibody

20-abx339404
  • EUR 493.20
  • EUR 360.00
  • 100 ul
  • 50 ul

Major Prion Protein (PRNP) Antibody (HRP)

20-abx319682
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prion Protein-Interacting Protein (PRNIP) Antibody

abx032619-400ul 400 ul
EUR 627.6

Prion Protein-Interacting Protein (PRNIP) Antibody

abx032619-80l 80 µl
EUR 343.2

Major Prion Protein (PRNP) Antibody (FITC)

20-abx336436
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Major Prion Protein (PRNP) Antibody (FITC)

20-abx319683
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prion Protein recombinant monoclonal antibody

A5436 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Prion Protein for WB, IHC,ELISA

Major Prion Protein (PRNP) Antibody (Biotin)

20-abx336437
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Major Prion Protein (PRNP) Antibody (Biotin)

20-abx319684
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse)

4-PAB680Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP)

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat)

4-PAB680Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP)

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), PE

4-PAB680Hu01-PE
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with PE.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), PE

4-PAB680Mu01-PE
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with PE.

Prion-Like Protein Doppel (Prnd) Antibody

abx236794-100ug 100 ug
EUR 661.2

Prion-Like Protein Doppel (PRND) Antibody

20-abx322158
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Prion-Like Protein Doppel (PRND) Antibody

20-abx320384
  • EUR 360.00
  • EUR 292.80
  • 100 ul
  • 50 ul

Prion-Like Protein Doppel (PRND) Antibody

20-abx006423
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
  • EUR 376.80
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC

4-PAB680Hu01-APC
  • EUR 399.60
  • EUR 3735.60
  • EUR 1046.40
  • EUR 507.60
  • EUR 258.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Cy3

4-PAB680Hu01-Cy3
  • EUR 483.60
  • EUR 4930.80
  • EUR 1345.20
  • EUR 627.60
  • EUR 294.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Cy3.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), HRP

4-PAB680Hu01-HRP
  • EUR 366.00
  • EUR 3256.80
  • EUR 926.40
  • EUR 459.60
  • EUR 243.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with HRP.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC

4-PAB680Mu01-APC
  • EUR 408.00
  • EUR 3843.60
  • EUR 1072.80
  • EUR 518.40
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAB680Mu01-Cy3
  • EUR 493.20
  • EUR 5074.80
  • EUR 1381.20
  • EUR 642.00
  • EUR 297.60
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Cy3.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), HRP

4-PAB680Mu01-HRP
  • EUR 373.20
  • EUR 3350.40
  • EUR 949.20
  • EUR 469.20
  • EUR 246.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with HRP.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), FITC

4-PAB680Hu01-FITC
  • EUR 344.40
  • EUR 3012.00
  • EUR 860.40
  • EUR 430.80
  • EUR 230.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with FITC.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), FITC

4-PAB680Mu01-FITC
  • EUR 350.40
  • EUR 3098.40
  • EUR 882.00
  • EUR 439.20
  • EUR 232.80
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with FITC.

Prion Protein Peptide

45-123P 0.1 mg
EUR 405.6
Description: (IN) Prion Protein (143-153) Peptide

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Biotinylated

4-PAB680Hu01-Biotin
  • EUR 363.60
  • EUR 2809.20
  • EUR 836.40
  • EUR 442.80
  • EUR 259.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Biotin.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAB680Mu01-Biotin
  • EUR 368.40
  • EUR 2888.40
  • EUR 856.80
  • EUR 450.00
  • EUR 260.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Biotin.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC-Cy7

4-PAB680Hu01-APC-Cy7
  • EUR 656.40
  • EUR 7327.20
  • EUR 1948.80
  • EUR 872.40
  • EUR 372.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC-Cy7.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC-Cy7

4-PAB680Mu01-APC-Cy7
  • EUR 672.00
  • EUR 7543.20
  • EUR 2002.80
  • EUR 894.00
  • EUR 378.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC-Cy7.

Prion Protein, RNA Aptamer

AR-316-U Custom Ask for price

Major Prion Protein (PRNP) Protein

20-abx263341
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

Mouse Prion Protein (PRNP) Protein

20-abx068666
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Prion Protein (PRNP) Protein

20-abx068667
  • EUR 828.00
  • EUR 343.20
  • EUR 2532.00
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Prion Protein 106-126 (human)

B5433-.5 500 µg
EUR 301.2

Prion Protein 106-126 (human)

B5433-1 1 mg
EUR 447.6

Prion Protein (106-126) (human)

H-1566.0500 0.5mg
EUR 327.6
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (106-126) (human)

H-1566.1000 1.0mg
EUR 501.6
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (118-135) (human)

H-4206.0001 1.0mg
EUR 691.2
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Prion Protein (118-135) (human)

H-4206.0005 5.0mg
EUR 2648.4
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Recombinant Prion Protein (PRNP)

4-RPB680Hu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Prion Protein expressed in: E.coli

Recombinant Prion Protein (PRNP)

4-RPB680Mu01
  • EUR 614.59
  • EUR 288.00
  • EUR 1974.72
  • EUR 738.24
  • EUR 1356.48
  • EUR 487.20
  • EUR 4756.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Prion Protein expressed in: E.coli

Rat Major prion protein (Prnp)

1-CSB-YP018739RA
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Major prion protein(Prnp) expressed in Yeast

Rat Major prion protein (Prnp)

1-CSB-EP018739RA
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Major prion protein(Prnp) expressed in E.coli

PRNP Prion Protein Human Recombinant Protein

PROTP04156 Regular: 10ug
EUR 380.4
Description: PRNP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (23-230a.a) and having a molecular mass of 25kDa. GOSR2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PRND Prion Protein 2Human Recombinant Protein

PROTQ9UKY0 Regular: 10ug
EUR 380.4
Description: PRND Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids (27-152a.a) and having a molecular mass of 58.5kDa. PRND is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Rat Prion Protein (PRNP) CLIA Kit

20-abx496530
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Prion Protein (106-126) (human) (scrambled)

H-4882.0500 0.5mg
EUR 327.6
Description: Sum Formula: C80H138N26O24S2; CAS# [150469-23-1] net

Prion Protein (106-126) (human) (scrambled)

H-4882.1000 1.0mg
EUR 501.6
Description: Sum Formula: C80H138N26O24S2; CAS# [150469-23-1] net

Rat Prion Protein (PRNP) ELISA Kit

20-abx258974
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Cow Prion Protein (PRNP) ELISA Kit

abx521103-96tests 96 tests
EUR 1093.2

Dog Prion Protein (PRNP) ELISA Kit

abx521105-96tests 96 tests
EUR 1093.2

Pig Prion Protein (PRNP) ELISA Kit

abx521108-96tests 96 tests
EUR 1093.2

Rat Prion Protein (PRNP) ELISA Kit

abx521109-96tests 96 tests
EUR 801.6

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x96wellstestplate 1x96-wells test plate
EUR 822.24
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-5x96wellstestplate 5x96-wells test plate
EUR 3340.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

4-SEB680Ra
  • EUR 6210.00
  • EUR 3280.80
  • EUR 823.20
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Prion Protein (PRNP) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Prion Protein (PRNP) CLIA Kit

20-abx492982
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Prion Protein (PRNP) CLIA Kit

20-abx492983
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-48T 48T
EUR 403.2

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-96T 96T
EUR 640.8

Mouse Prion Protein (PRNP) ELISA Kit

abx255159-96tests 96 tests
EUR 895.2

Human Prion Protein (PRNP) ELISA Kit

abx251835-96tests 96 tests
EUR 895.2

Human Prion Protein (PRNP) ELISA Kit

abx573091-96tests 96 tests
EUR 801.6

Mouse Prion Protein (PRNP) ELISA Kit

abx571234-96tests 96 tests
EUR 801.6

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

20-abx156738
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Prion Protein (PRNP) ELISA Kit

20-abx156832
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

4-SEB680Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

4-SEB680Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Prion Protein ELISA Kit (PRNP)

RK02138 96 Tests
EUR 625.2

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-48Tests 48 Tests
EUR 600

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-96Tests 96 Tests
EUR 830.4

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-48Tests 48 Tests
EUR 613.2

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-96Tests 96 Tests
EUR 850.8

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-48Tests 48 Tests
EUR 626.4

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-96Tests 96 Tests
EUR 868.8

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-48Tests 48 Tests
EUR 640.8

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-96Tests 96 Tests
EUR 890.4

Mouse Prion Protein ELISA Kit (PRNP)

RK03137 96 Tests
EUR 625.2

Human Prion Protein(PRNP)ELISA Kit

QY-E01716 96T
EUR 433.2

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-48T 48T
EUR 453.92
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-96T 96T
EUR 648.38
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-48T 48T
EUR 465.47
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-96T 96T
EUR 664.97
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-48T 48T
EUR 432.3
Description: tissue homogenates, cell lysates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-96T 96T
EUR 617.5
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-48T 48T
EUR 443.3
Description: tissue homogenates, cell lysates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-96T 96T
EUR 633.3
Description: tissue homogenates, cell lysates and other biological fluids.

Chicken Prion Protein (PRNP) ELISA Kit

abx521104-96tests 96 tests
EUR 1093.2

ELISA kit for Rat PRNP (Prion Protein)

ELK7722 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Prion Protein from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Mouse PRNP (Prion Protein)

ELK5103 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Prion Protein from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

ELISA kit for Human PRNP (Prion Protein)

ELK5129 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Prion Protein from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Pig Major prion protein(PRNP) ELISA kit

E07M0432-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Major prion protein(PRNP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Major prion protein(PRNP) ELISA kit

E07M0432-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Major prion protein(PRNP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Major prion protein(PRNP) ELISA kit

E07M0432-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Major prion protein(PRNP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Major prion protein(PRNP) ELISA kit

E08M0432-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Major prion protein(PRNP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Major prion protein(PRNP) ELISA kit

E08M0432-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Major prion protein(PRNP) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Collectively, these findings provide a way for monitoring the impact of a PrP-reducing drug within the CNS, and can facilitate growth of prion illness therapeutics with this mechanism of motion.

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