In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

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In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

Prion-like habits has been within the highlight because it was first related to the onset of mammalian neurodegenerative illnesses. Nevertheless, a rising physique of proof means that this mechanism may very well be behind the regulation of processes similar to transcription and translation in a number of species. Right here, we carry out a stringent computational survey to establish prion-like proteins within the human proteome. We detected 242 candidate polypeptides and computationally assessed their operate, protein-protein interplay networks, tissular expression, and their hyperlink to illness. Human prion-like proteins represent a subset of modular polypeptides broadly expressed throughout totally different cell varieties and tissues, considerably related to illness, embedded in extremely related interplay networks, and concerned within the stream of genetic data within the cell.

Our evaluation means that these proteins may play a related function not solely in neurological issues, but additionally in several types of most cancers and viral infections. Prion illnesses are quickly progressive neurodegenerative situations that may be tough to diagnose and are transmissible underneath particular circumstances. The authors will present background concerning prion illness and give attention to diagnostic instruments.Prion illness is brought on by misfolded prion protein. The three doable causes of prion illness embody sporadic (85%), genetic (10-15%), and purchased (<1%). Acquired prion illnesses embody kuru, iatrogenic, and variant Creutzfeldt-Jakob illness. Prion illnesses differ of their scientific manifestation, neuropathology, and diagnostic take a look at outcomes.

Quite a lot of latest diagnostic instruments have developed that enable extra dependable antemortem prognosis of prion illness similar to mind MRI and cerebrospinal fluid real-time quaking-induced conversion. Particular infectivity tips should be adopted when coping with central nervous system tissue, however solely normal precautions are wanted for routine scientific care of sufferers with prion illness.The one method to undoubtedly diagnose prion illness and decide its kind is by way of neuropathologic examination. Nevertheless, mind MRI and cerebrospinal fluid real-time quaking-induced conversion have drastically elevated diagnostic accuracy and are essential exams to make use of when evaluating sufferers with suspected prion illness.

Axonal modifications in experimental prion illnesses recapitulate these following constriction of postganglionic branches of the superior cervical ganglion: a comparability 40 years later.

The key neurological function of prion illnesses is a neuronal loss completed via both apoptosis or autophagy. On this evaluate, I in contrast axonal alterations in prion illnesses to these described 40 years earlier because of nerve ligation. I additionally demonstrated that autophagic vacuoles and autophagosomes are a significant a part of dystrophic neurites.

Moreover, I summarized the present standing of the autophagy in prion illnesses and hypothesize, that spongiform change might originate from the autophagic vacuoles. This conclusion must be supported by different strategies, specifically laser confocal microscopy. We noticed neuronal autophagic vacuoles in several phases of formation, and our interpretation of the ‘maturity’ of their formation might or might not equate to precise developmental phases. Initially, part of the neuronal cytoplasm was sequestrated inside double or a number of membranes (phagophores) and sometimes exhibited elevated electron-density.

The intracytoplasmic membranes shaped labyrinth-like buildings that counsel a multiplication of these membranes. The autophagic vacuoles then develop and ultimately, an enormous space of the cytoplasm was reworked right into a merging mass of autophagic vacuoles. Margaret R. Matthews revealed an extended treatise within the Philosophical Transactions of the Royal Society of London through which she had described in nice element the ultrastructure of postganglionic branches of the superior cervical ganglion within the rat following ligation of them. The earliest modifications noticed by Matthews between 6 h to 2 days within the proximal stump have been distensions of proximal axons. Analogously, in our fashions, an elevated variety of ‘common’ (spherical) and ‘irregular’ MVB and a few autophagic vacuoles have been noticed collectively, each processes have been comparable.

 In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.
In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

Prion protein quantification in human cerebrospinal fluid as a software for prion illness drug growth.

Discount of native prion protein (PrP) ranges within the mind is a beautiful technique for the remedy or prevention of human prion illness. Medical growth of any PrP-reducing therapeutic would require an acceptable pharmacodynamic biomarker: a sensible and sturdy methodology for quantifying PrP, and reliably demonstrating its discount within the central nervous system (CNS) of a residing affected person. Right here we consider the potential of ELISA-based quantification of human PrP in human cerebrospinal fluid (CSF) to function a biomarker for PrP-reducing therapeutics.

We present that CSF PrP is very delicate to plastic adsorption throughout dealing with and storage, however its loss may be minimized by the addition of detergent. We discover that blood contamination doesn’t have an effect on CSF PrP ranges, and that CSF PrP and hemoglobin are uncorrelated, collectively suggesting that CSF PrP is CNS derived, supporting its relevance for monitoring the tissue of curiosity and in step with excessive PrP abundance in mind relative to blood. In a cohort with managed pattern dealing with, CSF PrP displays good within-subject test-retest reliability (imply coefficient of variation, 13% in samples collected 8-11 wk aside), a sufficiently secure baseline to permit therapeutically significant reductions in mind PrP to be readily detected in CSF.

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EUR 419

Prion protein Antibody (PrP)

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abx139819-01mg 0.1 mg
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Major Prion Protein (CD230) Antibody

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Major Prion Protein (CD230) Antibody

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EUR 543.6

Major Prion Protein (CD230) Antibody

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Major Prion Protein (CD230) Antibody

abx412470-01ml 0.1 ml
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Prion Protein(PrP) Conjugated Antibody

C48939 100ul
EUR 476.4

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PA1794 100ug/vial
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Anti-Prion protein PrP/PRNP Antibody

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Cluster of Differentiation 230 Prion Protein Disease Form (CD230 PrPSc) Antibody

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PrP antibody

70R-PG004 100 ug
EUR 360
Description: Affinity purified Goat polyclonal PrP antibody

PrP Antibody

abx236812-100ug 100 ug
EUR 577.2

PrP Antibody

R35863-100UG 100 ug
EUR 399

anti- PrP antibody

FNab06812 100µg
EUR 606.3
Description: Antibody raised against PrP

Anti-PrP antibody

PAab06812 100 ug
EUR 426

PrP 27-30 antibody

20R-PG009 250 ul
EUR 418.8
Description: Goat polyclonal PrP 27-30 antibody

PrP 27-30 antibody

20-PG73 100 ul
EUR 600
Description: Goat polyclonal PrP 27-30 antibody

Prion Protein (PRNP) Antibody

20-abx101113
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  • EUR 159.60
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Prion Protein (PRNP) Antibody

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Prion Protein (PRNP) Antibody

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Prion Protein (PRNP) Antibody

abx120079-01ml 0.1 ml
EUR 1779.6

Prion Protein (PRNP) Antibody

20-abx114678
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Prion Protein (PRNP) Antibody

abx431521-200ul 200 ul
EUR 460.8

Polyclonal Prion Protein Antibody

APR12947G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Prion Protein . This antibody is tested and proven to work in the following applications:

PrP (106-126)

HY-P0305 10mg
EUR 1695.6

Prion Protein Peptide

45-123P 0.1 mg
EUR 405.6
Description: (IN) Prion Protein (143-153) Peptide

Prion Protein 2 (PRND) Antibody

20-abx114679
  • EUR 878.40
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Major Prion Protein (PRNP) Antibody

20-abx002019
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Prion Protein recombinant monoclonal antibody

A5436 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Prion Protein for WB, IHC,ELISA

Prion Protein (PRNP) Antibody Pair

20-abx370619
  • EUR 2264.40
  • EUR 1429.20
  • 10 × 96 tests
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Prion Protein (PRNP) Antibody Pair

20-abx370620
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  • 10 × 96 tests
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Prion Protein (PRNP) Antibody Pair

20-abx370621
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Major Prion Protein (PRNP) Antibody

20-abx333875
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  • 100 ug
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Major Prion Protein (PRNP) Antibody

20-abx319681
  • EUR 493.20
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Rabbit Anti-Haemophilus influenzae Type B PRP (Hib-PRP) antiserum

PRPB11-S 100 ul
EUR 548.4

Py-ds-Prp-Osu

ADC-L-017 unit Ask for price

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ADC-L-020 unit Ask for price

TCS PrP Inhibitor 13

B5402-10 10 mg
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B5402-25 25 mg
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B5402-5 5 mg
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Prion Protein-Interacting Protein (PRNIP) Antibody

abx032619-400ul 400 ul
EUR 627.6

Prion Protein-Interacting Protein (PRNIP) Antibody

abx032619-80l 80 µl
EUR 343.2

Anti-Prion

DB-033-0.05 50 μl
EUR 338.4

Anti-Prion

DB-033-0.1 100 μl
EUR 506.4

Anti-Prion

DB-080-0.05 50 μl
EUR 338.4

Anti-Prion

DB-080-0.1 100 μl
EUR 531.6

Anti-Prion

DB-081-0.05 50 μl
EUR 338.4

Anti-Prion

DB-081-0.1 100 μl
EUR 531.6

Prion Protein, RNA Aptamer

AR-316-U Custom Ask for price

Recombinant Prion Protein (PRNP)

4-RPB680Hu01
  • EUR 588.79
  • EUR 280.80
  • EUR 1877.95
  • EUR 705.98
  • EUR 1291.97
  • EUR 469.20
  • EUR 4514.88
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Prion Protein expressed in: E.coli

Recombinant Prion Protein (PRNP)

4-RPB680Mu01
  • EUR 614.59
  • EUR 288.00
  • EUR 1974.72
  • EUR 738.24
  • EUR 1356.48
  • EUR 487.20
  • EUR 4756.80
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Prion Protein expressed in: E.coli

Prion-Like Protein Doppel (PRND) Antibody

20-abx006423
  • EUR 493.20
  • EUR 710.40
  • EUR 218.40
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  • 100 ul
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Shadow of Prion Protein (SPRN) Antibody

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EUR 627.6

Shadow of Prion Protein (SPRN) Antibody

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Shadow Of Prion Protein (SPRN) Antibody

20-abx339404
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Major Prion Protein (PRNP) Antibody (HRP)

20-abx336435
  • EUR 493.20
  • EUR 2214.00
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  • EUR 218.40
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  • 100 ug
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Major Prion Protein (PRNP) Antibody (FITC)

20-abx336436
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
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Major Prion Protein (PRNP) Antibody (Biotin)

20-abx336437
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
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  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
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Major Prion Protein (PRNP) Antibody (HRP)

20-abx319682
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Major Prion Protein (PRNP) Antibody (FITC)

20-abx319683
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
  • EUR 360.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Major Prion Protein (PRNP) Antibody (Biotin)

20-abx319684
  • EUR 493.20
  • EUR 2214.00
  • EUR 718.80
  • EUR 218.40
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Prion-Like Protein Doppel (PRND) Antibody

20-abx320384
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  • EUR 292.80
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Prion-Like Protein Doppel (PRND) Antibody

20-abx322158
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  • EUR 292.80
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Prion-Like Protein Doppel (Prnd) Antibody

abx236794-100ug 100 ug
EUR 661.2

Anti-Prion Protein Rabbit Monoclonal Antibody

M02447 100ug/vial
EUR 476.4
Description: Rabbit Monoclonal Prion Protein Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-Prion Protein (143-153) antibody

STJ70951 100 µg
EUR 430.8

Mouse Prion Protein (PRNP) Protein

20-abx068666
  • EUR 861.60
  • EUR 343.20
  • EUR 2665.20
  • EUR 1028.40
  • EUR 610.80
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Prion Protein (PRNP) Protein

20-abx068667
  • EUR 828.00
  • EUR 343.20
  • EUR 2532.00
  • EUR 978.00
  • EUR 594.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Major Prion Protein (PRNP) Protein

20-abx263341
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

PACAP-Related Peptide (PRP), human

5-01701 4 x 1mg Ask for price

PACAP-Related Peptide (PRP), human

HY-P1511 1mg
EUR 280.8

Rat Major prion protein (Prnp)

1-CSB-YP018739RA
  • EUR 604.80
  • EUR 318.00
  • EUR 2198.40
  • EUR 915.60
  • EUR 1459.20
  • EUR 400.80
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Rat Major prion protein(Prnp) expressed in Yeast

Rat Major prion protein (Prnp)

1-CSB-EP018739RA
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
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Description: Recombinant Rat Major prion protein(Prnp) expressed in E.coli

Prion Protein 106-126 (human)

B5433-.5 500 µg
EUR 301.2

Prion Protein 106-126 (human)

B5433-1 1 mg
EUR 447.6

Prion Protein (118-135) (human)

H-4206.0001 1.0mg
EUR 691.2
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Prion Protein (118-135) (human)

H-4206.0005 5.0mg
EUR 2648.4
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Prion Protein (106-126) (human)

H-1566.0500 0.5mg
EUR 327.6
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (106-126) (human)

H-1566.1000 1.0mg
EUR 501.6
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Monoclonal Prion Antibody, Clone: EP1802Y

APR12946G 0.1ml
EUR 633.6
Description: A Monoclonal antibody against Human Prion. The antibodies are raised in Rabbit and are from clone EP1802Y. This antibody is applicable in WB and IHC

anti-Prion protein antibody mouse monoclonal (7A1)

65-903 50ug
EUR 355.2
Description: The anti-Prion protein antibody mouse monoclonal (7A1) is available in Europe and for worldwide shipping via Gentaur.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse)

4-PAB680Hu01
  • EUR 286.80
  • EUR 2869.20
  • EUR 717.60
  • EUR 358.80
  • EUR 253.20
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP)

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat)

4-PAB680Mu01
  • EUR 291.60
  • EUR 2948.40
  • EUR 735.60
  • EUR 366.00
  • EUR 254.40
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP)

Prion-like protein doppel Recombinant Protein

92-424 0.05 mg
EUR 651.3
Description: Prion-like protein doppel is a 152 amino acids protein that belongs to the prion family. The protein encoded by this gene is found on chromosome 20, approximately 20 kbp downstream of the gene encoding cellular prion protein, to which it is biochemically and structurally similar. It is a membrane glycosylphosphatidylinositol-anchored glycoprotein that is found predominantly in testis. Mutations in this gene may lead to neurological disorders.

Prion-Like Protein Doppel (PRND) Protein

20-abx263269
  • EUR 1930.80
  • EUR 393.60
  • EUR 276.00
  • 100 ug
  • 10 ug
  • 2 µg

PRND Prion Protein 2Human Recombinant Protein

PROTQ9UKY0 Regular: 10ug
EUR 380.4
Description: PRND Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids (27-152a.a) and having a molecular mass of 58.5kDa. PRND is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PRNP Prion Protein Human Recombinant Protein

PROTP04156 Regular: 10ug
EUR 380.4
Description: PRNP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (23-230a.a) and having a molecular mass of 25kDa. GOSR2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

neo PRP 10mg Plate SPE Columns

CHR5742 EACH
EUR 259.92

neo PRP 30mg/1mL SPE Columns

CHR5744 PK100
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neo PRP 150mg/6mL SPE Columns

CHR5756 PK30
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CHR5760 PK30
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neo PRP MPlate Pop Plate 5mg

CHR5938 EACH
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neo PRP MPlate Pop Plate 10mg

CHR5942 EACH
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Mouse Prion-like protein doppel (Prnd)

1-CSB-BP886153MO
  • EUR 711.60
  • EUR 306.00
  • EUR 1777.20
  • EUR 949.20
  • EUR 1303.20
  • EUR 416.40
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse Prion-like protein doppel(Prnd) expressed in Baculovirus

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-48T 48T
EUR 597.6
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-96T 96T
EUR 776.4
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-48T 48T
EUR 609.6
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-96T 96T
EUR 793.2
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

20-abx156738
  • EUR 8534.40
  • EUR 4550.40
  • EUR 1054.80
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Prion Protein (PRNP) ELISA Kit

20-abx156832
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Prion Protein (PRNP) ELISA Kit

20-abx258974
  • EUR 8684.40
  • EUR 4626.00
  • EUR 1074.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat Prion Protein (PRNP) CLIA Kit

20-abx496530
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Prion Protein (PRNP) ELISA Kit

abx571234-96tests 96 tests
EUR 801.6

Human Prion Protein (PRNP) ELISA Kit

abx573091-96tests 96 tests
EUR 801.6

Cow Prion Protein (PRNP) ELISA Kit

abx521103-96tests 96 tests
EUR 1093.2

Chicken Prion Protein (PRNP) ELISA Kit

abx521104-96tests 96 tests
EUR 1093.2

Dog Prion Protein (PRNP) ELISA Kit

abx521105-96tests 96 tests
EUR 1093.2

Pig Prion Protein (PRNP) ELISA Kit

abx521108-96tests 96 tests
EUR 1093.2

Rat Prion Protein (PRNP) ELISA Kit

abx521109-96tests 96 tests
EUR 801.6

Human Prion Protein (PRNP) CLIA Kit

20-abx492982
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Mouse Prion Protein (PRNP) CLIA Kit

20-abx492983
  • EUR 10282.80
  • EUR 5472.00
  • EUR 1262.40
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Prion Protein (PRNP) ELISA Kit

abx251835-96tests 96 tests
EUR 895.2

Mouse Prion Protein (PRNP) ELISA Kit

abx255159-96tests 96 tests
EUR 895.2

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-48T 48T
EUR 403.2

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-96T 96T
EUR 640.8

Prion Protein (106-126) (human) (scrambled)

H-4882.0500 0.5mg
EUR 327.6
Description: Sum Formula: C80H138N26O24S2; CAS# [150469-23-1] net

Prion Protein (106-126) (human) (scrambled)

H-4882.1000 1.0mg
EUR 501.6
Description: Sum Formula: C80H138N26O24S2; CAS# [150469-23-1] net

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-48Tests 48 Tests
EUR 600

Human Prion Protein (PRNP) ELISA Kit

RD-PRNP-Hu-96Tests 96 Tests
EUR 830.4

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-48Tests 48 Tests
EUR 613.2

Mouse Prion Protein (PRNP) ELISA Kit

RD-PRNP-Mu-96Tests 96 Tests
EUR 850.8

Human Prion Protein(PRNP)ELISA Kit

QY-E01716 96T
EUR 433.2

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-48Tests 48 Tests
EUR 626.4

Human Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Hu-96Tests 96 Tests
EUR 868.8

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-48Tests 48 Tests
EUR 640.8

Mouse Prion Protein (PRNP) ELISA Kit

RDR-PRNP-Mu-96Tests 96 Tests
EUR 890.4

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-10x96wellstestplate 10x96-wells test plate
EUR 5402.92
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x48wellstestplate 1x48-wells test plate
EUR 550.13
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x96wellstestplate 1x96-wells test plate
EUR 734.46
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-5x96wellstestplate 5x96-wells test plate
EUR 2945.08
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

4-SEB680Hu
  • EUR 5463.60
  • EUR 2886.00
  • EUR 735.60
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-10x96wellstestplate 10x96-wells test plate
EUR 5552.14
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x48wellstestplate 1x48-wells test plate
EUR 562.42
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x96wellstestplate 1x96-wells test plate
EUR 752.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-5x96wellstestplate 5x96-wells test plate
EUR 3024.07
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

4-SEB680Mu
  • EUR 5612.40
  • EUR 2965.20
  • EUR 752.40
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-10x96wellstestplate 10x96-wells test plate
EUR 6149.04
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x48wellstestplate 1x48-wells test plate
EUR 611.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Collectively, these findings provide a way for monitoring the impact of a PrP-reducing drug within the CNS, and can facilitate growth of prion illness therapeutics with this mechanism of motion.

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