In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

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In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

Prion-like habits has been within the highlight because it was first related to the onset of mammalian neurodegenerative illnesses. Nevertheless, a rising physique of proof means that this mechanism may very well be behind the regulation of processes similar to transcription and translation in a number of species. Right here, we carry out a stringent computational survey to establish prion-like proteins within the human proteome. We detected 242 candidate polypeptides and computationally assessed their operate, protein-protein interplay networks, tissular expression, and their hyperlink to illness. Human prion-like proteins represent a subset of modular polypeptides broadly expressed throughout totally different cell varieties and tissues, considerably related to illness, embedded in extremely related interplay networks, and concerned within the stream of genetic data within the cell.

Our evaluation means that these proteins may play a related function not solely in neurological issues, but additionally in several types of most cancers and viral infections. Prion illnesses are quickly progressive neurodegenerative situations that may be tough to diagnose and are transmissible underneath particular circumstances. The authors will present background concerning prion illness and give attention to diagnostic instruments.Prion illness is brought on by misfolded prion protein. The three doable causes of prion illness embody sporadic (85%), genetic (10-15%), and purchased (<1%). Acquired prion illnesses embody kuru, iatrogenic, and variant Creutzfeldt-Jakob illness. Prion illnesses differ of their scientific manifestation, neuropathology, and diagnostic take a look at outcomes.

Quite a lot of latest diagnostic instruments have developed that enable extra dependable antemortem prognosis of prion illness similar to mind MRI and cerebrospinal fluid real-time quaking-induced conversion. Particular infectivity tips should be adopted when coping with central nervous system tissue, however solely normal precautions are wanted for routine scientific care of sufferers with prion illness.The one method to undoubtedly diagnose prion illness and decide its kind is by way of neuropathologic examination. Nevertheless, mind MRI and cerebrospinal fluid real-time quaking-induced conversion have drastically elevated diagnostic accuracy and are essential exams to make use of when evaluating sufferers with suspected prion illness.

Axonal modifications in experimental prion illnesses recapitulate these following constriction of postganglionic branches of the superior cervical ganglion: a comparability 40 years later.

The key neurological function of prion illnesses is a neuronal loss completed via both apoptosis or autophagy. On this evaluate, I in contrast axonal alterations in prion illnesses to these described 40 years earlier because of nerve ligation. I additionally demonstrated that autophagic vacuoles and autophagosomes are a significant a part of dystrophic neurites.

Moreover, I summarized the present standing of the autophagy in prion illnesses and hypothesize, that spongiform change might originate from the autophagic vacuoles. This conclusion must be supported by different strategies, specifically laser confocal microscopy. We noticed neuronal autophagic vacuoles in several phases of formation, and our interpretation of the ‘maturity’ of their formation might or might not equate to precise developmental phases. Initially, part of the neuronal cytoplasm was sequestrated inside double or a number of membranes (phagophores) and sometimes exhibited elevated electron-density.

The intracytoplasmic membranes shaped labyrinth-like buildings that counsel a multiplication of these membranes. The autophagic vacuoles then develop and ultimately, an enormous space of the cytoplasm was reworked right into a merging mass of autophagic vacuoles. Margaret R. Matthews revealed an extended treatise within the Philosophical Transactions of the Royal Society of London through which she had described in nice element the ultrastructure of postganglionic branches of the superior cervical ganglion within the rat following ligation of them. The earliest modifications noticed by Matthews between 6 h to 2 days within the proximal stump have been distensions of proximal axons. Analogously, in our fashions, an elevated variety of ‘common’ (spherical) and ‘irregular’ MVB and a few autophagic vacuoles have been noticed collectively, each processes have been comparable.

 In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.
In silico Characterization of Human Prion-Like Proteins: Beyond Neurological Diseases.

Prion protein quantification in human cerebrospinal fluid as a software for prion illness drug growth.

Discount of native prion protein (PrP) ranges within the mind is a beautiful technique for the remedy or prevention of human prion illness. Medical growth of any PrP-reducing therapeutic would require an acceptable pharmacodynamic biomarker: a sensible and sturdy methodology for quantifying PrP, and reliably demonstrating its discount within the central nervous system (CNS) of a residing affected person. Right here we consider the potential of ELISA-based quantification of human PrP in human cerebrospinal fluid (CSF) to function a biomarker for PrP-reducing therapeutics.

We present that CSF PrP is very delicate to plastic adsorption throughout dealing with and storage, however its loss may be minimized by the addition of detergent. We discover that blood contamination doesn’t have an effect on CSF PrP ranges, and that CSF PrP and hemoglobin are uncorrelated, collectively suggesting that CSF PrP is CNS derived, supporting its relevance for monitoring the tissue of curiosity and in step with excessive PrP abundance in mind relative to blood. In a cohort with managed pattern dealing with, CSF PrP displays good within-subject test-retest reliability (imply coefficient of variation, 13% in samples collected 8-11 wk aside), a sufficiently secure baseline to permit therapeutically significant reductions in mind PrP to be readily detected in CSF.

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Description: Affinity purified Goat polyclonal PrP antibody

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anti- PrP antibody

FNab06812 100µg
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  • Immunogen: prion protein
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Description: Antibody raised against PrP

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Description: Goat polyclonal PrP 27-30 antibody

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Description: Goat polyclonal PrP 27-30 antibody

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Polyclonal Prion Protein Antibody

APR12947G 0.1ml
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Description: A polyclonal antibody raised in Chicken that recognizes and binds to Human Prion Protein . This antibody is tested and proven to work in the following applications:

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20-abx319681
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Prion Protein recombinant monoclonal antibody

A5436 100ul X 3
EUR 595
  • Comparisons between Mnoclonal, Polyclonal and Recombinant antibodies and their benefits: Regular monoclonal antibodies have higher purity, better specificity and less lot-to-lot variations than polyclonal antibodies. Recombinant antibodies, however,
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Description: A recombinant monoclonal antibody from rabbit against human Prion Protein for WB, IHC,ELISA

Major Prion Protein (PRNP) Antibody

20-abx002019
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TCS PrP Inhibitor 13

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Prion Protein-Interacting Protein (PRNIP) Antibody

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Anti-Prion

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Anti-Prion

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Recombinant Prion Protein (PRNP)

4-RPB680Hu01
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  • Uniprot ID: P04156
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.6kDa
  • Isoelectric Point: 9.5
Description: Recombinant Human Prion Protein expressed in: E.coli

Recombinant Prion Protein (PRNP)

4-RPB680Mu01
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  • Uniprot ID: P04925
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 26.8kDa
  • Isoelectric Point: 9.6
Description: Recombinant Mouse Prion Protein expressed in: E.coli

Prion-Like Protein Doppel (PRND) Antibody

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Shadow of Prion Protein (SPRN) Antibody

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Major Prion Protein (PRNP) Antibody (Biotin)

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Anti-Prion Protein Rabbit Monoclonal Antibody

M02447 100ug/vial
EUR 397
Description: Rabbit Monoclonal Prion Protein Antibody. Validated in Flow Cytometry, IF, IHC, ICC, WB and tested in Human, Mouse, Rat.

Anti-Prion Protein (143-153) antibody

STJ70951 100 µg
EUR 359

Mouse Prion Protein (PRNP) Protein

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Human Prion Protein (PRNP) Protein

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Major Prion Protein (PRNP) Protein

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PACAP-Related Peptide (PRP), human

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PACAP-Related Peptide (PRP), human

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anti-Prion protein antibody mouse monoclonal (7A1)

65-903 50ug
EUR 296
Description: The anti-Prion protein antibody mouse monoclonal (7A1) is available in Europe and for worldwide shipping via Gentaur.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse)

4-PAB680Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
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  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP)

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat)

4-PAB680Mu01
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  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP)

Rat Major prion protein (Prnp)

1-CSB-EP018739RA
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  • MW: 26.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rat Major prion protein(Prnp) expressed in E.coli

Rat Major prion protein (Prnp)

1-CSB-YP018739RA
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  • MW: 24.3 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Rat Major prion protein(Prnp) expressed in Yeast

Prion Protein 106-126 (human)

B5433-.5 500 µg
EUR 251

Prion Protein 106-126 (human)

B5433-1 1 mg
EUR 373

Prion Protein (106-126) (human)

H-1566.0500 0.5mg
EUR 273
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (106-126) (human)

H-1566.1000 1.0mg
EUR 418
Description: Sum Formula: C80H138N26O24S2; CAS# [148439-49-0] net

Prion Protein (118-135) (human)

H-4206.0001 1.0mg
EUR 576
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Prion Protein (118-135) (human)

H-4206.0005 5.0mg
EUR 2207
Description: Sum Formula: C68H112N18O22S2; CAS# [202121-03-7] net

Monoclonal Prion Antibody, Clone: EP1802Y

APR12946G 0.1ml
EUR 528
Description: A Monoclonal antibody against Human Prion. The antibodies are raised in Rabbit and are from clone EP1802Y. This antibody is applicable in WB and IHC

Prion-Like Protein Doppel (PRND) Protein

20-abx263269
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PRND Prion Protein 2Human Recombinant Protein

PROTQ9UKY0 Regular: 10ug
EUR 317
Description: PRND Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids (27-152a.a) and having a molecular mass of 58.5kDa. PRND is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

PRNP Prion Protein Human Recombinant Protein

PROTP04156 Regular: 10ug
EUR 317
Description: PRNP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 229 amino acids (23-230a.a) and having a molecular mass of 25kDa. GOSR2 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

anti-Prion protein antibody mouse monoclonal (2C5-5)

65-901 50ug
EUR 296
Description: The anti-Prion protein antibody mouse monoclonal (2C5-5) is available in Europe and for worldwide shipping via Gentaur.

Polyclonal Goat Anti-Prion Protein (143-153) Antibody

AMM05951G 0.1 mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-Prion Protein (143-153) . This antibody is tested and proven to work in the following applications:

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), APC

4-PAB680Hu01-APC
  • EUR 333.00
  • EUR 3113.00
  • EUR 872.00
  • EUR 423.00
  • EUR 215.00
  • 100ul
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  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with APC.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Biotinylated

4-PAB680Hu01-Biotin
  • EUR 303.00
  • EUR 2341.00
  • EUR 697.00
  • EUR 369.00
  • EUR 216.00
  • 100ul
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  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Biotin.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), Cy3

4-PAB680Hu01-Cy3
  • EUR 403.00
  • EUR 4109.00
  • EUR 1121.00
  • EUR 523.00
  • EUR 245.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with Cy3.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), FITC

4-PAB680Hu01-FITC
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with FITC.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), HRP

4-PAB680Hu01-HRP
  • EUR 305.00
  • EUR 2714.00
  • EUR 772.00
  • EUR 383.00
  • EUR 203.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with HRP.

Prion Protein (PRNP) Polyclonal Antibody (Rat, Mouse), PE

4-PAB680Hu01-PE
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00
  • EUR 359.00
  • EUR 192.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Rat, Mouse Prion Protein (PRNP). This antibody is labeled with PE.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), APC

4-PAB680Mu01-APC
  • EUR 340.00
  • EUR 3203.00
  • EUR 894.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with APC.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Biotinylated

4-PAB680Mu01-Biotin
  • EUR 307.00
  • EUR 2407.00
  • EUR 714.00
  • EUR 375.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Biotin.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), Cy3

4-PAB680Mu01-Cy3
  • EUR 411.00
  • EUR 4229.00
  • EUR 1151.00
  • EUR 535.00
  • EUR 248.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with Cy3.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), FITC

4-PAB680Mu01-FITC
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with FITC.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), HRP

4-PAB680Mu01-HRP
  • EUR 311.00
  • EUR 2792.00
  • EUR 791.00
  • EUR 391.00
  • EUR 205.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with HRP.

Prion Protein (PRNP) Polyclonal Antibody (Mouse, Rat), PE

4-PAB680Mu01-PE
  • EUR 292.00
  • EUR 2582.00
  • EUR 735.00
  • EUR 366.00
  • EUR 194.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: PRNP (Lys23~Ser230)
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Mouse, Rat Prion Protein (PRNP). This antibody is labeled with PE.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-48T 48T
EUR 498
  • Should the Human Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Hu-96T 96T
EUR 647
  • Should the Human Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-48T 48T
EUR 508
  • Should the Mouse Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

DLR-PRNP-Mu-96T 96T
EUR 661
  • Should the Mouse Prion Protein (PRNP) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates or other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

20-abx156738
  • EUR 7112.00
  • EUR 3792.00
  • EUR 879.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Prion Protein (PRNP) ELISA Kit

20-abx156832
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Mouse Prion Protein (PRNP) ELISA Kit

abx255159-96tests 96 tests
EUR 746
  • Shipped within 5-12 working days.

Rat Prion Protein (PRNP) ELISA Kit

20-abx258974
  • EUR 7237.00
  • EUR 3855.00
  • EUR 895.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Shipped within 5-7 working days.

Human Prion Protein (PRNP) ELISA Kit

abx251835-96tests 96 tests
EUR 746
  • Shipped within 5-12 working days.

Cow Prion Protein (PRNP) ELISA Kit

abx521103-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Chicken Prion Protein (PRNP) ELISA Kit

abx521104-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Dog Prion Protein (PRNP) ELISA Kit

abx521105-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Pig Prion Protein (PRNP) ELISA Kit

abx521108-96tests 96 tests
EUR 911
  • Shipped within 5-12 working days.

Rat Prion Protein (PRNP) ELISA Kit

abx521109-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

Mouse Prion Protein (PRNP) ELISA Kit

abx571234-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

Human Prion Protein (PRNP) ELISA Kit

abx573091-96tests 96 tests
EUR 668
  • Shipped within 5-12 working days.

Human Prion Protein (PRNP) CLIA Kit

20-abx492982
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Mouse Prion Protein (PRNP) CLIA Kit

20-abx492983
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Rat Prion Protein (PRNP) CLIA Kit

20-abx496530
  • EUR 8569.00
  • EUR 4560.00
  • EUR 1052.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests
  • Please enquire.

Mouse Prion-like protein doppel (Prnd)

1-CSB-BP886153MO
  • EUR 593.00
  • EUR 255.00
  • EUR 1481.00
  • EUR 791.00
  • EUR 1086.00
  • EUR 347.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
  • MW: 18.9 kDa
  • Buffer composition: Tris-based buffer with 50% glycerol.
Description: Recombinant Mouse Prion-like protein doppel(Prnd) expressed in Baculovirus

Prion Protein (106-126) (human) (scrambled)

H-4882.0500 0.5mg
EUR 273
Description: Sum Formula: C80H138N26O24S2; CAS# [150469-23-1] net

Prion Protein (106-126) (human) (scrambled)

H-4882.1000 1.0mg
EUR 418
Description: Sum Formula: C80H138N26O24S2; CAS# [150469-23-1] net

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-48T 48T
EUR 336

Bovine Prion Protein(PP) ELISA Kit

GA-E0040BV-96T 96T
EUR 534

Human Prion Protein(PRNP)ELISA Kit

QY-E01716 96T
EUR 361

Human Prion Protein ELISA Kit (PRNP)

RK02138 96 Tests
EUR 521

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-10x96wellstestplate 10x96-wells test plate
EUR 4502.43
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x48wellstestplate 1x48-wells test plate
EUR 458.44
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-1x96wellstestplate 1x96-wells test plate
EUR 612.05
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

SEB680Hu-5x96wellstestplate 5x96-wells test plate
EUR 2454.23
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Human Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Prion Protein (PRNP) ELISA Kit

4-SEB680Hu
  • EUR 4553.00
  • EUR 2405.00
  • EUR 613.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Prion Protein elisa. Alternative names of the recognized antigen: CD230
  • GSS
  • ASCR
  • CJD
  • PRIP
  • PrP
  • PrP2730
  • PrPc
  • Major prion protein
  • Creutzfeldt-Jakob Disease
  • Gerstmann-Strausler-Scheinker Syndrome
  • Fatal Familial Insomnia
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-10x96wellstestplate 10x96-wells test plate
EUR 4626.78
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x48wellstestplate 1x48-wells test plate
EUR 468.68
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-1x96wellstestplate 1x96-wells test plate
EUR 626.68
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

SEB680Mu-5x96wellstestplate 5x96-wells test plate
EUR 2520.06
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Prion Protein (PRNP) in tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Mouse Prion Protein (PRNP) ELISA Kit

4-SEB680Mu
  • EUR 4677.00
  • EUR 2471.00
  • EUR 627.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Prion Protein elisa. Alternative names of the recognized antigen: CD230
  • GSS
  • ASCR
  • CJD
  • PRIP
  • PrP
  • PrP2730
  • PrPc
  • Major prion protein
  • Creutzfeldt-Jakob Disease
  • Gerstmann-Strausler-Scheinker Syndrome
  • Fatal Familial Insomnia
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Prion Protein (PRNP) in samples from tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-10x96wellstestplate 10x96-wells test plate
EUR 5124.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x48wellstestplate 1x48-wells test plate
EUR 509.64
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-1x96wellstestplate 1x96-wells test plate
EUR 685.2
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

SEB680Ra-5x96wellstestplate 5x96-wells test plate
EUR 2783.4
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Rat Prion Protein (PRNP) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Prion Protein (PRNP) in tissue homogenates, cell lysates and other biological fluids.

Rat Prion Protein (PRNP) ELISA Kit

4-SEB680Ra
  • EUR 5175.00
  • EUR 2734.00
  • EUR 686.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Prion Protein elisa. Alternative names of the recognized antigen: CD230
  • GSS
  • ASCR
  • CJD
  • PRIP
  • PrP
  • PrP2730
  • PrPc
  • Major prion protein
  • Creutzfeldt-Jakob Disease
  • Gerstmann-Strausler-Scheinker Syndrome
  • Fatal Familial Insomnia
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Prion Protein (PRNP) in samples from tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Mouse Prion Protein ELISA Kit (PRNP)

RK03137 96 Tests
EUR 521

Collectively, these findings provide a way for monitoring the impact of a PrP-reducing drug within the CNS, and can facilitate growth of prion illness therapeutics with this mechanism of motion.

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