An embedded gene choice methodology utilizing knockoffs optimizing

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An embedded gene choice methodology utilizing knockoffs optimizing neural community

 

Background: Gene alternative refers to find a small subset of discriminant genes from the gene expression profiles. The best way to decide on genes that affect specific phenotypic traits efficiently is an important evaluation work throughout the topic of biology. The neural neighborhood has increased turning into functionality when dealing with nonlinear data, and it’ll in all probability seize choices robotically and flexibly. On this work, we propose an embedded gene alternative methodology using neural neighborhood.

 

The important genes could also be obtained by calculating the burden coefficient after the teaching is achieved. In an effort to treatment the difficulty of black area of neural neighborhood and extra make the teaching outcomes interpretable in neural neighborhood, we use the idea of knockoffs to assemble the knockoff attribute genes of the distinctive attribute genes. This technique not solely make each attribute gene to compete with each other, however moreover make each attribute gene compete with its knockoff attribute gene. This methodology might assist to choose the essential factor genes that affect the decision-making of neural networks.

 

Outcomes: We use maize carotenoids, tocopherol methyltransferase, raffinose family oligosaccharides and human breast most cancers dataset to do verification and analysis.

 

Conclusions: The experiment outcomes show that the knockoffs optimizing neural neighborhood methodology has increased detection impression than the alternative current algorithms, and particularly for processing the nonlinear gene expression and phenotype data.

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prionics

 

Fenretinide

A3412-5.1 10 mM (in 1mL DMSO)
EUR 113.00
Description: Fenretinide(4HPR) is an inhibitor of Focal adhesion kinase (FAK) [1].Fenretinideis a vitamin A analogue, it has been shown toinhibit the growth of many tumor cells, including small-cell lung cancer, malignant hemopoietic cells, and breast cancer cells.

Fenretinide

A3412-50 50 mg
EUR 152.00
Description: Fenretinide(4HPR) is an inhibitor of Focal adhesion kinase (FAK) [1].Fenretinideis a vitamin A analogue, it has been shown toinhibit the growth of many tumor cells, including small-cell lung cancer, malignant hemopoietic cells, and breast cancer cells.

Fenretinide

HY-15373 10mM/1mL
EUR 126.00

Fenretinide

GP8861-10MG 10 mg
EUR 94.00

Fenretinide

GP8861-25MG 25 mg
EUR 142.00

 

Single cell transcriptomes reveal expression patterns of chemoreceptor genes in olfactory sensory neurons of the Caribbean spiny lobster, Panulirus argus

 

 

Background: Crustaceans categorical numerous programs of receptor genes of their antennules, which house olfactory sensory neurons (OSNs) and non-olfactory chemosensory neurons. Transcriptomics analysis reveal that candidate chemoreceptor proteins embrace variant Ionotropic Receptors (IRs) along with every co-receptor IRs and tuning IRs, Transient Receptor Potential (TRP) channels, Gustatory Receptors, epithelial sodium channels, and class A G-protein coupled receptors (GPCRs). The Caribbean spiny lobster, Panulirus argus, expresses in its antennules virtually 600 IRs, 17 TRP channels, 1 Gustatory Receptor, 7 epithelial sodium channels, 81 GPCRs, 6 G proteins, and dozens of enzymes in signaling pathways.

 

However, the exact combinatorial expression patterns of these proteins in single sensory neurons normally usually are not acknowledged for any crustacean, limiting our understanding of how their chemosensory strategies encode chemical top quality.

 

Outcomes: The aim of this analysis was to utilize transcriptomics to clarify expression patterns of chemoreceptor genes in OSNs of P. argus. We generated and analyzed transcriptomes from 7 single OSNs, a couple of of which have been confirmed to reply a meals odor, along with an additional 7 multicell transcriptomes from preparations containing few (2-4), numerous (ca. 15), or many (ca. 400) OSNs. We found that each OSN expressed the similar 2 co-receptor IRs (IR25a, IR93a) nevertheless

 

not the alternative 2 antennular coIRs (IR8a, IR76b), 9-53 tuning IRs nevertheless only one to some in extreme abundance, the similar 5 TRP channels plus as a lot as 5 further TRPs, 12-17 GPCRs along with the similar 5 expressed in every single cell transcriptome, the similar Three G proteins plus others, many enzymes throughout the signaling pathways, nevertheless no Gustatory Receptors or epithelial sodium channels. The perfect distinction in receptor expression among the many many OSNs was the identification of the tuning IRs.

 

Conclusions: Our outcomes current an preliminary view of the combinatorial expression patterns of receptor molecules in single OSNs in a single species of decapod crustacean, along with receptors straight involved in olfactory transduction and others likely involved in modulation. Our outcomes moreover counsel variations in receptor expression in OSNs vs. completely different chemosensory neurons.

Camel Genetic Belongings Conservation by Tourism: A Key Sociocultural Methodology of Camelback Leisure Driving

 

  • Camels are distinctive components, which can be comprised inside journey journey companies promoting ecotourism actions. Such recreations contribute to sustainable livelihoods for native communities and educational empowerment within the route of nature and its conservation. At present, some native camel breeds’ survival reduces to this animal-based leisure enterprise and its reliability to hold out and promote custom-made corporations By conducting an on-site questionnaire to prospects collaborating in camelback driving excursions, we assessed the motivational parts affecting participation, satisfaction, and loyalty on this tourism section that can have made it socially differentiated.

 

  • The sixfold combination of employees effectivity, custom geography, quite a few and humane shut interaction, camel conduct and effectivity, sociotemporal context, and constructive earlier experience consists of the elemental dimensions that designate purchaser satisfaction and return intention probability inside this leisure enterprise.

 

  • Purchaser knowledge is essential for stakeholders to assemble personalised driving experiences and align earnings with environmental sustainability and biodiversity mainstream concerns into their frequently operations. In flip, house camel vacationer rides may be managed as a viable path to nature conservation by serving to endangered native breeds to stay away from their helpful devaluation and potential extinction.

 

gel casting base 20 cm

EVS1300-BASE ea
EUR 200.00

gel casting base for evs3100

EVS3100-BASE ea
EUR 301.00

gel casting base for evs3200

EVS3200-BASE ea
EUR 301.00

gel casting base for evs3300

EVS3300-BASE ea
EUR 301.00

Vatalanib, Free Base

2026-25
EUR 305.00

Vatalanib, Free Base

2026-5
EUR 126.00

Erlotinib, Free Base

2048-100
EUR 158.00

Erlotinib, Free Base

2048-1000
EUR 387.00

Linsitinib, Free base

2294-25
EUR 566.00

Linsitinib, Free base

2294-5
EUR 185.00

Tipifarnib, Free base

2296-1
EUR 142.00

Tipifarnib, Free base

2296-5
EUR 414.00

Sunitinib, Free base

2097-100
EUR 191.00

Sunitinib, Free base

2097-1000
EUR 501.00

Sunitinib, Free base

2097-25
EUR 115.00

Lapatinib, Free base

2138-100
EUR 387.00

Lapatinib, Free base

2138-25
EUR 191.00

Ruxolitinib, Free base

2139-100 Ask for price

Ruxolitinib, Free base

2139-25
EUR 533.00

Ruxolitinib, Free base

2139-5
EUR 207.00

Imatinib, Free base

2141-100
EUR 147.00

Imatinib, Free base

2141-1000
EUR 419.00

Apatinib (Free base)

B1613-25
EUR 414.00

Apatinib (Free base)

B1613-5
EUR 142.00

Carubicin (Free base)

B1853-1
EUR 153.00

Carubicin (Free base)

B1853-5
EUR 457.00

FIPI (free base)

B2372-25
EUR 631.00

FIPI (free base)

B2372-5
EUR 196.00

Terbinafine (Free base)

B2423-250
EUR 207.00

Terbinafine (Free base)

B2423-50
EUR 120.00

MCC950 (Free base)

B1031-1
EUR 153.00

MCC950 (Free base)

B1031-5
EUR 457.00

THZ1 (Free base)

9664-25
EUR 1023.00

THZ1 (Free base)

9664-5
EUR 294.00

R406(free base)

E1KS1533 2mg
EUR 521.00

AZD4547, Free Base

ADC-P-063 unit Ask for price

AZD8055, Free Base

ADC-P-064 unit Ask for price

Cyclopamine, Free Base

ADC-P-079 unit Ask for price

Ixabepilone, Free Base

ADC-P-104 unit Ask for price

R406 (free base)

A5880-100 100 mg
EUR 1210.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-25 25 mg
EUR 514.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-5 5 mg
EUR 166.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-5.1 10 mM (in 1mL DMSO)
EUR 264.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

R406 (free base)

A5880-S Evaluation Sample
EUR 81.00
Description: R406 is a potent SYK inhibitorSpleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase mainly expressed in hematopoietic cells. It transmits signals from a variety of cell surface receptors including CD74, Fc receptor and integrins.

Rucaparib (free base)

A8893-10 10 mg
EUR 200.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-200 200 mg
EUR 1036.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-5 5 mg
EUR 137.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-5.1 10 mM (in 1mL DMSO)
EUR 142.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

Rucaparib (free base)

A8893-50 50 mg
EUR 456.00
Description: Rucaparib, also named as AG-014699 or PF-01367338, is a poly (ADP ribose) polymerase (PARP) inhibitor. PARP is a DNA damage-activated nuclear enzyme that has a key signaling role in the base excision repair pathway.

LY2835219 free base

A3575-100 100 mg
EUR 572.00
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

LY2835219 free base

A3575-25 25 mg
EUR 258.00
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

LY2835219 free base

A3575-5 5 mg
EUR 142.00
Description: LY2835219 is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.

RPR107393 free base

HY-100299 1mg
EUR 481.00

FR167344 free base

HY-100301 1mg
EUR 2637.00

FR183998 free base

HY-100302 1mg
EUR 1127.00

FR194738 free base

HY-100303 1mg
EUR 1990.00

ITI214 (free base)

HY-12501 100mg
EUR 2943.00

AS2863619 (free base)

HY-126675 5mg
EUR 1175.00

AZD3839 (free base)

HY-13438 50mg
EUR 1014.00

Ripasudil free base

HY-15685A 10mg
EUR 408.00

Vatalanib (free base)

HY-10203 5mg
EUR 119.00

Masupirdine (free base)

HY-109118 1mg
EUR 223.00

R406 (free base)

HY-11108 10mM/1mL
EUR 231.00

YM158 (free base)

HY-U00355 1mg
EUR 2309.00

Xylazine (free base)

Q-1445.0025 25.0g
EUR 321.00
Description: Sum Formula: C12H16N2S; CAS# [7361-61-7]

TMB free base

TB0954 1g
EUR 70.88
  • Product category: Biochemicals/Indicators/Stains/Immuno Related

PLX5622 (free base)

B2965-25 25 mg
EUR 753.00

PLX5622 (free base)

B2965-5 5 mg
EUR 227.00

RGB-286638,  free base

2886-25
EUR 756.00

RGB-286638,  free base

2886-5
EUR 229.00

StemRegenin 1, Free base

2642-1
EUR 131.00

StemRegenin 1, Free base

2642-5
EUR 332.00

GSK-J4 (Free base)

2762-1
EUR 120.00

GSK-J4 (Free base)

2762-5
EUR 262.00

BMS-345541 (Free base)

B1907-1
EUR 142.00

BMS-345541 (Free base)

B1907-5
EUR 414.00

UNC-926, free base

B2158-25
EUR 631.00

UNC-926, free base

B2158-5
EUR 196.00

SB-334867 free base

B3423-100 100 mg
EUR 599.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base

B3423-25 25 mg
EUR 290.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base

B3423-5 5 mg
EUR 128.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

SB-334867 free base

B3423-5.1 10 mM (in 1mL DMSO)
EUR 131.00
Description: SB-334867 free base is a selective antagonist of orexin-1 receptor [1].Orexin-A and orexin-B are two peptides isolated from rat hypothalamus. They are involved in some physiological functions such as the control of feeding, energy metabolism and regulation of the sleep-wake cycle.

BMS-345541(free base)

B4655-10 10 mg
EUR 235.00
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

BMS-345541(free base)

B4655-5 5 mg
EUR 171.00
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

BMS-345541(free base)

B4655-50 50 mg
EUR 595.00
Description: BMS-345541(free base) is a selective inhibitor of IKK-1 and IKK-2 with IC50 value of 4?M and 0.3?M, respectively [1].IKK is also known as nuclear factor kappa-B kinase subunit inhibitor and involves in cytokine-activated intracellular signaling pathways.

GSK J4 free base

B5959-10 10 mg
EUR 373.00
Description: GSK J4 free base

GSK J4 free base

B5959-50 50 mg
EUR 1198.00
Description: GSK J4 free base

Staurosporine, >99% Free Base

BC090-001 1mg
EUR 246.00

Staurosporine, >99% Free Base

BC090-005 5mg
EUR 340.00

Vandetanib, >99% Free Base

BC098-025 25mg
EUR 232.00

Vandetanib, >99% Free Base

BC098-050 50mg
EUR 286.00

Vandetanib, >99% Free Base

BC098-100 100mg
EUR 313.00

Vandetanib, >100% Free Base

BC098-500 500mg
EUR 658.00

L-Arginine free base

AB0205 100g
EUR 63.15
  • Product category: Biochemicals/Amino Acids/Derivatives

SGI-1776 free base

A4192-10 10 mg
EUR 247.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-5 5 mg
EUR 154.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-5.1 10 mM (in 1mL DMSO)
EUR 166.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-50 50 mg
EUR 525.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

SGI-1776 free base

A4192-S Evaluation Sample
EUR 81.00
Description: SGI-1776 free base, N-((1-methylpiperidin-4-yl)methyl)-3-(3-(trifluoromethoxy)phenyl)imidazo[1,2-b]pyridazin-6-amine, is a potent ATP-competitive inhibitor of the serine/threonine family of Pim kinase, an enzyme regulating cell survival.

AM-095 free base

A3167-10 10 mg
EUR 212.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-100 100 mg
EUR 804.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-200 200 mg
EUR 1152.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-5 5 mg
EUR 166.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

AM-095 free base

A3167-50 50 mg
EUR 572.00
Description: AM095 is a novel, potent and orally bioavailable antagonist of lysophosphatidic acid type 1 receptor (LPA1) with IC50 values of 0.73 and 0.98 ?M for mouse or recombinant human LPA1, respectively [1].

FK-448 Free base

HY-100193 10mg
EUR 1887.00

KW-8232 free base

HY-100304 10mg
EUR 5018.00

YM-53601 free base

HY-100313 1mg
EUR 1559.00

APX-115 (free base)

HY-120801A 5mg
EUR 223.00

LY-2584702 (free base)

HY-12493 5mg
EUR 165.00

Genz-123346 (free base)

HY-12744 10mM/1mL
EUR 189.00

YHO-13351 (free base)

HY-12758A 10mM/1mL
EUR 176.00

JTV-519 (free base)

HY-15293A 5mg
EUR 567.00

RGB-286638 (free base)

HY-15504A 100mg
EUR 2804.00

DOV-216,303 (Free Base)

HY-18332C 10mM/1mL
EUR 492.00

CP-319340(free base)

HY-U00270 5mg
EUR 877.00

AV-412 (free base)

HY-10346A 5mg
EUR 173.00

SB-334867 (free base)

HY-10895A 10mg
EUR 215.00

SNT-207858 (free base)

HY-11030A 10mg
EUR 911.00

Z-NHNH2 (free base)

Q-1150.0025 25.0g
EUR 126.00
Description: Sum Formula: C8H10N2O2; CAS# [5331-43-1]

Z-NHNH2 (free base)

Q-1150.0100 100.0g
EUR 321.00
Description: Sum Formula: C8H10N2O2; CAS# [5331-43-1]

Afatinib

A170-100MG 100mg
EUR 102.00

Afatinib

HY-10261 200mg
EUR 312.00

BAY 58-2667 (Free base)

2452-1
EUR 354.00

BAY 58-2667 (Free base)

2452-5
EUR 1132.00

BAY 43-9006, Free base

2142-100
EUR 419.00

BAY 43-9006, Free base

2142-25
EUR 169.00

EZSolution? StemRegenin 1, Free base

2643-1
EUR 142.00

H-Tyr-OEt (free base)

E-2900.0025 25.0g
EUR 139.00
Description: Sum Formula: C11H15NO3; CAS# [949-67-7]

H-Tyr-OEt (free base)

E-2900.0100 100.0g
EUR 357.00
Description: Sum Formula: C11H15NO3; CAS# [949-67-7]

Biotin ethylenediamine (free base form)

90071 25MG
EUR 132.00
Description: Minimum order quantity: 1 unit of 25MG

biotin cadaverine, free base form

90079 50MG
EUR 215.00
Description: Minimum order quantity: 1 unit of 50MG

SB 202190, >99% Free Base

BC086-025 25mg
EUR 205.00

SB 202190, >99% Free Base

BC086-050 50mg
EUR 246.00

SB 203580, >99% Free Base

BC087-025 25mg
EUR 219.00

SB 203580, >99% Free Base

BC087-050 50mg
EUR 286.00

Gastrofensin AN 5 free base

HY-100296 5mg
EUR 2120.00

Glyoxalase I inhibitor (free base)

HY-15167A 50mg
EUR 2530.00

Bay 65-1942 (free base)

HY-50949 10mg
EUR 1069.00

Afatinib (BIBW2992)

A8247-10 10 mg
EUR 221.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-5 5 mg
EUR 147.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-5.1 10 mM (in 1mL DMSO)
EUR 244.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-50 50 mg
EUR 512.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib (BIBW2992)

A8247-S Evaluation Sample
EUR 81.00
Description: Afatinib (BIBW2992), an irreversible inhibitor of the ErbB family of tyrosine kinases, downregulates ErbB signalling by binding to the kinase domains of epidermal growth factor receptor (EGFR)/ human epidermal growth factor receptor 2 (HER2) with IC50 of 0.5 nM and 14nM, respectively.

Afatinib dimaleate

A3145-10 10 mg
EUR 221.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib dimaleate

A3145-5 5 mg
EUR 147.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib dimaleate

A3145-5.1 10 mM (in 1mL DMSO)
EUR 119.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib dimaleate

A3145-50 50 mg
EUR 512.00
Description: Afatinib is an irreversible EGFR/HER2 inhibitor with an IC50 of 14 nM for in vitro potency against HER2.

Afatinib (dimaleate)

HY-10261A 200mg
EUR 312.00

Human Free PSA (f-PSA) ELISA Kit

PRB-5049-FREE 96 assays
EUR 572.00

H-Arg(Mtr)-OtBu (free base)

E-3075.0001 1.0g
EUR 309.00
Description: Sum Formula: C20H34N4O5S; CAS# [115608-61-2]

H-Arg(Mtr)-OtBu (free base)

E-3075.0005 5.0g
EUR 1143.00
Description: Sum Formula: C20H34N4O5S; CAS# [115608-61-2]

H-Arg(Pmc)-OtBu (free base)

E-3085.0001 1.0g
EUR 418.00
Description: Sum Formula: C24H40N4O5S; CAS# [169543-81-1]

H-Arg(Pmc)-OtBu (free base)

E-3085.0005 5.0g
EUR 1554.00
Description: Sum Formula: C24H40N4O5S; CAS# [169543-81-1]

biotin-x cadaverine, free base form

90080 20MG
EUR 215.00
Description: Minimum order quantity: 1 unit of 20MG

PNU-282987 (S enantiomer free base)

HY-12560D 5mg
EUR 1014.00

Cyclosporin A-Derivative 1 (Free base)

HY-P1355A 1mg
EUR 223.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-002 2 mg
EUR 178.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-005 5 mg
EUR 265.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-010 10 mg
EUR 315.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-025 25 mg
EUR 394.00

CHIR 99021, GSK-3 Inhibitor , Free Base

BC212-100 100 mg
EUR 887.00

H-Ala-Ala-Phe-AMC (free base)

I-1415.0050 50.0mg
EUR 151.00
Description: Sum Formula: C25H28N4O5; CAS# [62037-41-6]

H-Ala-Ala-Phe-AMC (free base)

I-1415.0250 250.0mg
EUR 515.00
Description: Sum Formula: C25H28N4O5; CAS# [62037-41-6]

Human Free PSA (f-PSA) ELISA Kit

PRB-5049-FREE-5 5 x 96 assays
EUR 2283.00

(D-Ser(tBu)6,Azagly10)-LHRH (free base)

H-7296.0005 5.0mg
EUR 183.00
Description: Sum Formula: C59H84N18O14; CAS# [65807-02-5]

(D-Ser(tBu)6,Azagly10)-LHRH (free base)

H-7296.0025 25.0mg
EUR 641.00
Description: Sum Formula: C59H84N18O14; CAS# [65807-02-5]

Tris-base

20-abx082498
  • EUR 328.00
  • EUR 203.00
  • EUR 411.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

casting base

EHS3100-CAST ea
EUR 107.00

casting base

EHS3200-CAST ea
EUR 124.00

casting base

EHS3300-CAST ea
EUR 124.00

Rimonabant base

GX9120-10MG 10 mg
EUR 86.00

Rimonabant base

GX9120-25MG 25 mg
EUR 130.00

Tetracycline base

GA9779-100G 100 g
EUR 150.00

Tetracycline base

GA9779-10G 10 g
EUR 46.00

Tetracycline base

GA9779-25G 25 g
EUR 62.00

ProteoIQ Base

PS2 1
EUR 4262.00

Vincamine base

Q-1435.0005 5.0g
EUR 225.00
Description: Sum Formula: C21H26N2O3; CAS# [1617-90-9]

Vincamine base

Q-1435.0025 25.0g
EUR 803.00
Description: Sum Formula: C21H26N2O3; CAS# [1617-90-9]

CETRIMIDE AGAR BASE

C03-107-10kg 10 kg
EUR 1229.00

CETRIMIDE AGAR BASE

C03-107-2Kg 2 Kg
EUR 306.00

CETRIMIDE AGAR BASE

C03-107-500g 500 g
EUR 120.00

Fuchsine base (monohydrochloride)

HY-B1539A 1g
EUR 119.00

Rhodamine B base

GT5360-100G 100 g
EUR 158.00

Rhodamine B base

GT5360-10G 10 g
EUR 50.00

Rhodamine B base

GT5360-25G 25 g
EUR 70.00

Rhodamine B base

GT5360-50G 50 g
EUR 102.00

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