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Understanding Prion Strains: Evidence from Studies of the Disease Forms Affecting Humans.

Understanding Prion Strains: Evidence from Studies of the Disease Forms Affecting Humans.

Prion illnesses are a novel group of uncommon neurodegenerative problems characterised by tissue deposition of heterogeneous aggregates of abnormally folded protease-resistant prion protein (PrPSc), a broad spectrum of illness phenotypes and a variable effectivity of illness propagation in vivo. The dominant clinicopathological phenotypes of human prion illness embody Creutzfeldt⁻Jakob illness, deadly insomnia, variably protease-sensitive prionopathy, […]