Optimization Of Digital Pcr Master Mix

N-Flux™ 5X Digital PCR Master Mix

31078-1 KT
EUR 443

Human IgG antibody Laboratories manufactures the optimization of digital pcr master mix reagents distributed by Genprice. The Optimization Of Digital Pcr Master Mix reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact MasterMix PCR. Other Optimization products are available in stock. Specificity: Optimization Category: Of Group: Digital Pcr

amfiSure PCR Master Mix

10X50 rxns
EUR 262.8

amfiSure PCR Master Mix

10x1ml
EUR 343.2

amfiSure PCR Master Mix

15X50 rxns
EUR 333.6

amfiSure PCR Master Mix

20x1ml
EUR 562.8

amfiSure PCR Master Mix

50x50 rxns
EUR 902.4

amfiSure PCR Master Mix

100x50 rxns
EUR 1509.6

amfiXpand PCR Master Mix

2X50 rxns
EUR 181.2

Digital Pcr information

INTELLI-PLATE 48-well optimization plate; 120 plates

MAR-102-0002-00 120 PLATES
EUR 990
Description: INTELLI-PLATE 48-well optimization plate; 120 plates

Sample Diluent Optimization Pack: 100mL SD1, SD2, SD3, PFSD

959 pack
EUR 187

Cell Line Optimization 4D-Nucleofector X Kit (64 RXN)

LOV4XC-9064 each
EUR 889.41

PROTAC® Optimization Kit for PARP1-Cereblon Binding

78441 384 rxns.
EUR 995
Description: The PROTAC Optimization Kit for PARP1-Cereblon Binding is designed for the testing and profiling of PROTACs directed against PARP1 and Cereblon (CRBN). This Kit comes in a convenient AlphaLISA™ format, with the PARP1 Degrader iRucaparib-AP6 (PROTAC) added as positive control, PARP1 buffer, purified PARP1 and CRBN proteins for 384 reactions. The PARP1 inhibitor Rucaparib is included as a control that blocks PROTAC binding to PARP1. With this kit, three simple steps are required for the measurement of PROTAC activity. First, the PROTAC of interest is incubated with CRBN and PARP1. Next, acceptor beads are added, then donor beads, followed by reading of the Alpha-counts.Illustration of the assay principle: A PROTAC of interest or positive control iRucaparib-AP6 (PROTAC) interacts with both PARP1 and CRBN, bringing them in close proximity. PARP1 contains a GST tag, recognized by the GSH donor bead, while CRBN contains a FLAG tag that binds to the AlphaLISA™ acceptor bead conjugated with an anti-FLAG antibody. Upon excitation of the donor bead, a singlet oxygen is generated by the donor bead. The singlet oxygen excites the acceptor bead and emits light proportionally to the level of interaction. AlphaLISA™ immunoassays are a no-wash alternative to ELISA immunoassays. These assays are robust and ideal for a minimal hands-on approach.

PROTAC® Optimization Kit for IRAK4-Cereblon Binding

78512 384 rxns.
EUR 860
Description: The PROTAC Optimization Kit for IRAK4-Cereblon Binding is designed for the testing and profiling of PROTACs directed against IRAK4 and Cereblon (CRBN). The IRAK4 ligand-1 is included as a control that blocks PROTAC binding to IRAK4. With this kit, only three simple steps are required for the measurement of PROTAC activity. First, the PROTAC of interest is incubated with CRBN and IRAK4. Next, acceptor beads are added, then donor beads, followed by reading of the Alpha-counts. Illustration of the assay principle: A PROTAC of interest or positive control IRAK4 Degrader-1 (PROTAC) interacts with both IRAK4 and CRBN, bringing them in close proximity. IRAK4 contains a GST-tag, recognized by the GSH donor bead, while CRBN contains a FLAG-tag that binds to the AlphaLISA™ acceptor bead conjugated with an anti-FLAG antibody. Upon excitation of the donor bead, a singlet oxygen is generated by the donor bead, which excites the acceptor bead and emits light proportionally to the level of interaction. AlphaLISA™ immunoassays are a no-wash alternative to ELISA immunoassays. These assays are robust and ideal for a minimal hands-on approach.

Nucleofector 2b Cell Line Optimization Kit, 18 reactions

LOVCO-1001N each
EUR 480.98

Cell Line Optimization 96-well Nucleofector Kit (96 RXN)

LOV4SC-9096 each
EUR 1140.84

PROTAC Optimization Kit for CDK Kinase-Cereblon Binding

79924 384 rxns.
EUR 860
Description: The PROTAC Optimization Kit for CDK Kinase-Cereblon Binding is designed for testing and profiling of PROTACs directed against the CDK Kinase family and Cereblon. Cereblon (CRBN) is a Substrate recognition component of the DCX (DDB1-CUL44-Rbx1) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

The CDK inhibitor Palbociclib is included as a control inhibitor of PROTAC binding to CDK. With this kit, only three simple steps on a microtiter plate are required for PROTAC activity detection. First, a sample containing PROTAC is incubated with CRBN and CDK4 or CDK6 Kinase. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

Primary Cell Optimization 4D-Nucleofector X Kit (96 RXN)

LOV4XP-9096 each
EUR 1422.7

Primary Cell Optimization 4D-Nucleofector Y Kit (AD1+AD2)

LOV4YP-9A48 each
EUR 1062.75

Immobilization Buffer Optimization Kit – 10 mM Acetate (20 mL)

NIIMB-OPT each
EUR 212.55

Primary Cell Optimization 96-well Nucleofector Kit (96 RXN)

LOV4SP-9096 each
EUR 2374.71

PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding

79770 384 rxns.
EUR 995
Description: The PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding is designed for testing and profiling of PROTACs directed against BET Bromodomain family and Cereblon complex. Cereblon (CRBN) is a Substrate recognition component of a DCX (DDB1-CUL44-Rbx1) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins._x000D_ The PROTAC Optimization Kit for BET Bromodomain-Cereblon Binding comes in a convenient AlphaLISA® format, with dBET1 PROTAC, Immuno Buffer 1, and purified BRD3(BD2) and CRBN for 384 reactions. (+)JQ1 is included as a control inhibitor of PROTAC binding to BRD3(BD2). With this kit, only three simple steps on a microtiter plate are required for PROTAC activity detection. First, a sample containing PROTAC is incubated with CRBN and BRD3(BD2), one of BET bromodomains. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts._x000D_

MTO1, CT (Mitochondrial Translation Optimization 1 Homolog, CGI-02)

MBS6004520-005mg 0.05(mg
EUR 745

MTO1, CT (Mitochondrial Translation Optimization 1 Homolog, CGI-02)

MBS6004520-5x005mg 5x0.05mg
EUR 3195

PROTAC Optimization Kit for BET Bromodomain-Von Hippel Lindau (VHL) Binding

79790 384 rxns.
EUR 860
Description: The PROTAC Optimization Kit for BET Bromodomain-Von Hippel Lindau (VHL) Binding is designed for testing and profiling PROTACs directed against the BET Bromodomain family and VHL complex. VHL is a substrate recognition component of E3 protein ligase complex and is linked by Elongin C to a heterodimeric Cul2/Rbx1 module, which functions as a potent activator of the ubiquitination of target proteins by an E2 conjugating enzyme. Elongin B interacts with the complex through Elongin C and stabilizes the binding of Elongin C to VHL. Mutations in VHL are associated with the inherited von Hippel-Lindau cancer syndrome and numerous forms of renal cell carcinoma. With this kit, only three simple steps on a microtiter plate are required for PROTAC activity
detection. First, a sample containing PROTAC is incubated with VHL and BRD3(BD2), one of the
BET bromodomains. Next, acceptor beads are added, then donor beads, followed by reading the Alpha-counts.

Mto1 (GFP-tagged) - Mouse mitochondrial translation optimization 1 homolog (S

MG206766 10 µg Ask for price