Quick product search

diseases-solutions/besnoitiosis/Besnoitiosisdiseases-solutions/bluetongue/Bluetonguediseases-solutions/bovine-viral-diarrhoea/Bovine Viral Diarrhoeadiseases-solutions/brucellosis/Brucellosisfileadmin/user_upload/downloads_and_prints/01I475_H_BRSV_detection.pdfBRSVfileadmin/user_upload/data/doc/Ingezim_products/Crypto_technical_datasheet.pdfCryptosporidiosis diseases-solutions/bovine-viral-diarrhoea/enzootic-bovine-leukosis/Enzootic Bovine Leukosisdiseases-solutions/foot-and-mouth-disease/Foot and Mouth Diseasefileadmin/user_upload/downloads_and_prints/Leaflet_L_Hardjo_01.pdfLeptospirosisfileadmin/user_upload/data/doc/Prionics_Product_list.pdfNeosporosis diseases-solutions/paratuberculosis/Paratuberculosisfileadmin/user_upload/data/doc/Prionics_Product_list.pdfRotavirus diseases-solutions/salmonellosis/Salmonellosisdiseases-solutions/tse/TSEtuberculosis/Tuberculosis
diseases-solutions/african-swine-fever/African Swine Feverfileadmin/user_upload/data/doc/Prionics_Product_list.pdfAPPdiseases-solutions/classical-swine-fever/Classical Swine Feverfileadmin/user_upload/data/doc/Ingezim_products/Crypto_technical_datasheet.pdfCryptosporidiosis fileadmin/user_upload/data/doc/Ingezim_products/Erysipelas_technical_datasheet.pdfErysipelas diseases-solutions/foot-and-mouth-disease/Foot and Mouth Diseasefileadmin/user_upload/data/doc/Prionics_Product_list.pdfGlasser's Disease diseases-solutions/hepatitis-e-virus/Hepatitis E Virusdiseases-solutions/mycobacterium-avium/Mycobacterium Aviumfileadmin/user_upload/downloads_and_prints/pri_LF_PPV_Ab.pdfPorcine Parvo Virushttp://www.prionics.com/fileadmin/user_upload/data/doc/Prionics_Product_list.pdfPPEdiseases-solutions/porcine-reproductive-and-respiratory-syndrome/PRRSdiseases-solutions/pseudorabies/Pseudorabiesfileadmin/user_upload/data/doc/Prionics_Product_list.pdfRotavirus diseases-solutions/salmonellosis/Salmonellosisfileadmin/user_upload/data/doc/Ingezim_products/MHyo_technical_datasheet.pdfSwine Enzootic Pneumonia fileadmin/user_upload/data/doc/Prionics_Product_list.pdfSwine Dysentry fileadmin/user_upload/data/doc/Ingezim_products/Influenza_A_swine_technical_datasheet.pdfSwine Influenza diseases-solutions/swine-vesicular-disease/Swine Vesicular Diseasediseases-solutions/toxoplasmosis/Toxoplasmosisfileadmin/user_upload/data/doc/Ingezim_products/Coronavirus_TGEV_differential_technical_datasheet.pdfTGEV and Corona Virus diseases-solutions/trichinellosis/Trichinellosis
diseases-solutions/bluetongue/Bluetonguediseases-solutions/brucellosis/Brucellosisfileadmin/user_upload/data/doc/Ingezim_products/Crypto_technical_datasheet.pdfCryptosporidosis diseases-solutions/foot-and-mouth-disease/Foot and Mouth Diseasediseases-solutions/paratuberculosis/Paratuberculosisfileadmin/user_upload/data/doc/Prionics_Product_list.pdfRotavirus diseases-solutions/toxoplasmosis/Toxoplasmosistuberculosis/Tuberculosis
diseases-solutions/african-horse-sickness/African Horse Sicknessfileadmin/user_upload/data/doc/Ingezim_products/Crypto_technical_datasheet.pdfCryptosporidiosis fileadmin/user_upload/data/doc/Ingezim_products/Equine_artherithis_virus_technical_datasheet.pdfEquine Arteritisfileadmin/user_upload/data/doc/Prionics_Product_list.pdfEq. Viral Rhinopneumonitis fileadmin/user_upload/data/doc/Prionics_Product_list.pdfRotavirus fileadmin/user_upload/data/doc/Ingezim_products/West_nile_compac_technical_datasheet.pdfWest Nile Virus
diseases-solutions/cervids/TSE
tuberculosis/Tuberculosis
417
http://www.prionics.com/

Stimune: A Highly Effective Immunogenic Adjuvant

  • Effective and safe adjuvant system
  • Strongly increased antibody production in mice and other species

  • Antibody yields can be more than 10x higher than with other adjuvants

  

About Stimune

Stimune is a water-in-oil adjuvant, which was developed at the Animal Sciences Group (ID -Lelystad) in Lelystad, The Netherlands. The adjuvant has been extensively tested by the Animal Sciences Group and other laboratories and can be used to immunize a range of animals including birds, mice, guinea pigs, rabbits, pigs and goats. The mineral oil based emulsion is fortified with protein exposing reagents, allowing Stimune to elicit strong immune reactions.



Stimune can be applied both subcutaneously and intramuscularly.

Effective and safe

Stimune is a safe adjuvant that elicits a strong immune response, resulting in high antibody yields. Because of its efficacy, Stimune could reduce the number of animals used.

Side effects of Stimune application have been tested extensively in pigs, piglets and rabbits. Additionally, a pyrogenicity test was performed in rabbits according to the European Pharmacopoeia. The side effects following immunization are negligible. The adjuvant is non-pyrogenic and only slight degeneration of muscular tissue is sometimes observed at the immunization site.

Stringent quality control ensures product consistency, purity and biological activity, enabling scientists to use Stimune with confidence.

Intended use

Four parts of the water phase containing the antigen is mixed with 5 parts Stimune (v/v). See table below for the preferable dose per immunization. Stimune can be stored with the antigen at 5 3C for at least one year without loss of activity.

Preferable dose per immunization:

Mice

0.1 ml

Chicken

0.5 ml

Guinea pigs and rats

0.5 ml

Rabbits, goats and pigs  

1.0 ml

 

Stimune is intended FOR RESEARCH PURPOSES ONLY

Proven adjuvant

Stimune is a proven adjuvant that has been in use since 1985 and has been commercially available since 1996. It is a potent adjuvant, eliciting a strong immune response in B cells. Antibody yields can be more than tenfold higher than with other adjuvants. This has been shown with various antigens and in a range of animal models including parakeets and rabbits.

 

Stimune (2x20 ml)
Prod. No. 7925000


Available in
prionics-shop.com:
 
Order here!

Selected Reading

Beck I et al., (2003) 
Vaccine 21:1006-1022

 

Bokhout BA et al., (1981) 
Vet Immunol Immunopathol. 2:491-500